Meta-analysis of the relation of body mass index to all-cause and cardiovascular mortality and hospitalization in patients with chronic heart failure

The American Journal of Cardiology
Abhishek SharmaJason M Lazar

Abstract

Clinical studies have indicated the existence of an "obesity paradox" in patients with chronic heart failure (HF), that is, reduced mortality in patients who have elevated body mass index (BMI) scores compared with normal-weight reference groups. The aim of this study was to investigate the relation of BMI with all-cause and cardiovascular (CV) mortality and hospitalization in patients with chronic HF though a systematic review and meta-analysis of published research. PubMed, the Cumulative Index to Nursing and Allied Health Literature, Cochrane Central, Scopus, web of science and Embase were searched for studies reporting rates of total mortality, cardiac mortality, and risk for hospitalization in patients with HF in various BMI categories (<20 kg/m(2) [low], 20 to 24.9 kg/m(2) [normal reference], 25 to 29.9 kg/m(2) [overweight], 30 to 34.9 [obese], and ≥35 kg/m(2) [severely obese]). Event rates were compared using a forest plot of relative risk (RR) using a random-effects model assuming interstudy heterogeneity. Two study investigators independently reviewed the 124 reports retrieved and identified 6 for final analyses (n = 22,807). After a mean follow-up period of 2.85 years, the risk for adverse events was highest in patien...Continue Reading

References

Jul 26, 1990·The New England Journal of Medicine·B LevineM Packer
Oct 19, 2000·Lancet·M RauchhausS D Anker
Apr 2, 2003·The American Journal of Cardiology·Carl J LavieMandeep R Mehra
Oct 14, 2003·Journal of Applied Physiology·Fulvio LauretaniLuigi Ferrucci
May 4, 2004·Journal of the American College of Cardiology·Mandeep R MehraEdward D Frohlich
Jul 13, 2007·European Heart Journal·Abel Romero-CorralFrancisco Lopez-Jimenez
Jul 1, 2008·American Heart Journal·Antigone OreopoulosFinlay A McAlister
Feb 4, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·D O OkoroduduF Lopez-Jimenez
Nov 10, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Sanae HamaguchiUNKNOWN JCARE-CARD Investigators
Nov 1, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·R PadwalA Bayes-Genis
Mar 14, 2014·JACC. Heart Failure·Carl J LavieHector O Ventura
Feb 3, 2015·American Heart Journal·Carl J LavieRoss Arena

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Citations

Feb 15, 2016·JACC. Heart Failure·Carl J LavieRoss Arena
Jan 31, 2016·Progress in Cardiovascular Diseases·Carl J LavieRichard V Milani
Jan 2, 2016·Progress in Cardiovascular Diseases·Carl J LavieHector O Ventura
Feb 24, 2016·Journal of Obesity·Emmanuel Aja Oga, Olabimpe Ruth Eseyin
Mar 5, 2016·JACC. Heart Failure·Carl J Lavie, Hector O Ventura
Oct 27, 2015·Journal of Cardiac Failure·Kenneth E Freedland
Mar 26, 2016·Pharmacology & Therapeutics·Yingmei Zhang, Jun Ren
Oct 12, 2015·JACC. Heart Failure·Carl J Lavie, Hector O Ventura
Aug 25, 2015·Current Heart Failure Reports·Ambarish PandeyCarl J Lavie
Apr 5, 2016·Biochimica Et Biophysica Acta·Stephen C Kolwicz
Apr 28, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Fernanda Donner AlvesAndréia Biolo
May 18, 2016·The American Journal of Cardiology·Marco ProiettiGregory Y H Lip
Jun 10, 2016·Journal of Veterinary Internal Medicine·F R RomanoL M Freeman
Jun 21, 2016·International Journal of Cardiology·M Marcinkiewicz-SiemionK A Kaminski
Jun 19, 2016·Journal of Cardiac Failure·Carl J Lavie, Hector O Ventura
Jul 14, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A S AntonopoulosD Tousoulis
Feb 18, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S MazimbaK C Bilchick
Apr 1, 2017·European Heart Journal. Acute Cardiovascular Care·Akiomi YoshihisaUNKNOWN Acute Decompensated Heart Failure Syndromes (ATTEND) investigators
Oct 28, 2016·Journal of Cardiovascular Pharmacology and Therapeutics·Luis SargentoRoberto Palma Dos Reis
Apr 6, 2017·São Paulo Medical Journal = Revista Paulista De Medicina·Camila WeschenfelderCatarina Bertaso Andreatta Gottschall
Jan 28, 2017·Scientific Reports·In-Seok SongJun-Beom Park
Dec 3, 2016·JACC. Heart Failure·Emer JoyceUNKNOWN Heart Failure Apprentice Network
Jul 28, 2017·Nature Reviews. Cardiology·Carl J LavieHector O Ventura
Jul 18, 2017·Expert Review of Cardiovascular Therapy·Marcela Rodriguez FloresPaul Poirier
Feb 23, 2018·The Journal of International Medical Research·Mohamad JarrahIssa M Hweidi
Jan 28, 2018·Journal of Epidemiology and Community Health·Steven D StovitzJay S Kaufman
Jan 20, 2018·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M JiR An
Mar 2, 2018·Computers, Informatics, Nursing : CIN·Eliezer Bose, Kavita Radhakrishnan
Sep 30, 2017·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·D Kilov, G Kilov
Dec 9, 2017·Journal of Neurosurgery·Neha S DangayachStephan A Mayer
Jul 3, 2018·European Journal of Heart Failure·Koen W StrengChim C Lang

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