PMID: 22336615Feb 18, 2012Paper

Meta-analysis on the association between subclinical hypothyroidism and the left ventricular functions under Doppler echocardiography

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Xin ChenJing-pu Shi

Abstract

To explore the association between subclinical hypothyroidism and the left ventricular functions under conventional 2D Doppler echocardiography and to provide evidence for the protection of heart function. Literatures regarding the association of subclinical hypothyroidism and the left ventricular functions were retrieved in large databases from home and abroad for the last 12 years. The left ventricular systolic function was assessed by left ventricular ejection fraction and the shortening of left ventricular fraction. The left ventricular diastolic function was assessed by left ventricular early diastolic filling flow velocity, late diastolic filling flow velocity, their ratios (E/A), and the left ventricular isovolumic relaxation time. The relationship between subclinical hypothyroidism and the left ventricular functions were assessed by Meta-analysis with Stata 11 software. The weighted mean difference (WMD) and 95% confidence interval (CI) were calculated, and the publication bias was assessed by Begg's test. 13 eligible papers were included. (1) Statistics on the combined data showed that in the evaluation of left ventricular diastolic function indicators. There were significant differences in left ventricular late diasto...Continue Reading

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