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Metabolic acidosis: pathophysiology, diagnosis and management

Nature Reviews. Nephrology

May 1, 2010

Jeffrey A Kraut, Nicolaos E Madias

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Abstract

Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO(2)) of approximately 1 mmHg for every 1 mmol/l fall in serum HCO(3)(-) concentration, and a reduction ...read more

Mentioned in this Paper

Anion Gap Measurement
Organic acids, Gynecological
Acidosis
Hypotension Adverse Event
Carbonic Acid Ions
Cardiovascular System
Acute Disease
Lactic Acid Measurement
Low Cardiac Output
Cachexia
23
1
343
Paper Details
References
    • References58
    • Citations56
    • References58
    • Citations56
  • Metabolic acidosis: pathophysiology, diagnosis and management

    Nature Reviews. Nephrology

    May 1, 2010

    Jeffrey A Kraut, Nicolaos E Madias

    PMID: 20308999

    DOI: 10.1038/nrneph.2010.33

    Abstract

    Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO(2)) of approximately 1 mmHg for every 1 mmol/l fall in serum HCO(3)(-) concentration, and a reduction ...read more

    Mentioned in this Paper

    Anion Gap Measurement
    Organic acids, Gynecological
    Acidosis
    Hypotension Adverse Event
    Carbonic Acid Ions
    23
    1
    343

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    References
    • References58
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