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Metabolic acidosis: pathophysiology, diagnosis and management

Nature Reviews. Nephrology

Mar 24, 2010

Jeffrey A Kraut, Nicolaos E Madias

Abstract

Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO(2)) of approximately 1 mmHg for every 1 mmol/l fall in serum HCO(3)(-) concentration, and a reduction ...read more

Mentioned in this Paper

Wasting
Immune Response
Organic acids, Gynecological
Serum Bicarbonate Measurement
Keto Acids
Cardiovascular System
Serum Anion Gap Measurement
Pathological Dilatation
Anion Gap Measurement
Carbonic Acid Ions
23
1
373
1
Paper Details
References
  • References92
  • Citations67
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  • References92
  • Citations67
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Related Papers

Nature Reviews. Nephrology

Treatment of acute metabolic acidosis: a pathophysiologic approach

Nature Reviews. NephrologySeptember 5, 2012
Jeffrey A Kraut, Nicolaos E Madias
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Metabolic acidosis: pathophysiology, diagnosis and management

Nature Reviews. Nephrology

Mar 24, 2010

Jeffrey A Kraut, Nicolaos E Madias

PMID: 20308999

DOI: 10.1038/nrneph.2010.33

Abstract

Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO(2)) of approximately 1 mmHg for every 1 mmol/l fall in serum HCO(3)(-) concentration, and a reduction ...read more

Mentioned in this Paper

Wasting
Immune Response
Organic acids, Gynecological
Serum Bicarbonate Measurement
Keto Acids
Cardiovascular System
Serum Anion Gap Measurement
Pathological Dilatation
Anion Gap Measurement
Carbonic Acid Ions
23
1
373
1

Similar Papers Found In These Feeds

Cachexia & Brown Fat

Cachexia is a condition associated with progressive weight loss due to severe illness. In cancer patients, it is proposed to occur as a result of tumor-induced energy wasting. Several proteins have been implicated in browning and depletion of white adipose tissue. Here is the latest research on cachexia and brown fat.

Neural Circuitry & Cachexia

Cytokines released during inflammation and malignancy act on the central nervous system to alter the release and function of a number of neurotransmitters, thereby altering both appetite and metabolic rate, leading to the rise of cachexia. Discover the latest research on neural circuitry and cachexia here

Related Papers

Nature Reviews. Nephrology

Treatment of acute metabolic acidosis: a pathophysiologic approach

Nature Reviews. NephrologySeptember 5, 2012
Jeffrey A Kraut, Nicolaos E Madias
Paper Details
References
  • References92
  • Citations67
12345...
  • References92
  • Citations67
12345...
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