PMID: 2124371Jan 1, 1990Paper

Metabolic activity in the calcified zone of cartilage: observations on tetracycline labelled articular cartilage in human osteoarthritic hips

Rheumatology International
P A RevellF Walker

Abstract

The tidemark is a metabolically active zone in the calcified layer of the cartilage in which it is possible to show that there is calcifying activity even over a short period of time using a tetracycline labelling technique. The tidemark slowly advances in the direction of the non-calcified cartilage and analysis of double-tetracycline labelled cartilage shows that this is not an appositional phenomenon like that occurring in bone, but that, where present, several tidemarks can be labelled at the same time. Each tidemark may therefore be metabolically active and it is not just the tidemark adjacent to hyaline cartilage which incorporates calcium.

References

May 1, 1988·The Journal of Bone and Joint Surgery. British Volume·K M SamuelsonP A Revell
Jan 1, 1983·The Journal of Bone and Joint Surgery. British Volume·P G Bullough, A Jagannath
Aug 1, 1980·The Journal of Bone and Joint Surgery. British Volume·L B Lane, P G Bullough

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Citations

May 19, 2005·Journal of Molecular Histology·T J LyonsJ McClure
Dec 23, 1998·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·I SchiefkeG Leutert
Oct 26, 2005·Osteoarthritis and Cartilage·K P H PritzkerW B van den Berg
Jul 10, 2013·Osteoarthritis and Cartilage·A RoschgerC Streli
May 13, 2011·Archives of Oral Biology·R ChenX Long
Feb 12, 2013·Foot & Ankle International·Olaf BuettnerVictor Valderrabano
May 15, 1997·Microscopy Research and Technique·T R OegemaR C Thompson
May 15, 1997·Microscopy Research and Technique·J DequekerS Boonen
May 15, 1997·Microscopy Research and Technique·D L GardnerK Oates
May 3, 2012·The Journal of Rheumatology·Peter A Simkin
Oct 3, 2018·RMD Open·Louise Brøndt HartlevEllen-Margrethe Hauge
Oct 18, 2003·Analytical and Bioanalytical Chemistry·M J RobertsM E Brezinski
Feb 5, 2000·Equine Veterinary Journal. Supplement·R C MurrayP Lekeux
May 24, 2019·Osteoarthritis and Cartilage·F MaierD M Pierce
Jun 5, 2021·Calcified Tissue International·Alan Boyde

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