Metabolic and genetic disorders mimicking cerebral palsy.

Neurosciences : the Official Journal of the Pan Arab Union of Neurological Sciences
Wejdan S HakamiBrahim M Tabarki

Abstract

Cerebral palsy is a syndrome that encompasses a large group of childhood movement and posture disorders that result from a lesion occurring in the developing brain. The clinical presentation of many metabolic and genetic conditions, particularly in highly consanguineous populations, can mimic cerebral palsy particularly at early age. The aim of this review article is to identify the clinical features that should alert the physician to the possibility of disorders that resemble cerebral palsy, the clinical and neuroimaging red flags, and highlight some metabolic and genetic conditions which may present with spasticity, ataxia and dyskinesia. In the case of metabolic or genetic disorder, making a precise diagnosis is particularly important for the possibility of treatment, accurate prognosis and genetic counseling.

Citations

Aug 27, 2021·Frontiers in Pediatrics·John AllenEleanor J Molloy

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