Metabolic and molecular stress responses of sublittoral bearded horse mussel Modiolus barbatus to warming sea water: implications for vertical zonation

The Journal of Experimental Biology
Andreas AnestisBasile Michaelidis

Abstract

The present study set out to investigate the thermal limits of the Mediterranean bivalve Modiolus barbatus, acclimated to various temperatures, and includes a comparison of laboratory determined limits with its temperature-dependent restriction to deeper water layers in its natural habitat. Thermal responses and limits were determined by integrating information from various levels of biological organization, including the expression of Hsp70 and Hsp90, the phosphorylation of stress-activated protein kinases, p38 mitogen-activated protein kinase (p38 MAPK) and cJun-N-terminal kinases (JNKs) as well as metabolic adjustments. The latter were assessed by examining temperature effects on the activity of the key glycolytic enzyme pyruvate kinase (PK). The expression of Hsp70 and Hsp90 was activated when mussels were acclimated to temperatures above 20 degrees C. Increased phosphorylation of p38 MAPK and JNKs at about the same temperatures indicate activation of MAPK signaling cascades and their potential involvement in the induction of Hsp genes. As indicated by the activity of PK, Modiolus barbatus maintains some aerobic capacity when acclimated to temperatures up to 24 degrees C, while further warming probably caused metabolic depr...Continue Reading

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Citations

Dec 28, 2012·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Konstantinos FeidantsisBasile Michaelidis
Feb 13, 2010·Annual Review of Physiology·Gretchen E Hofmann, Anne E Todgham
Apr 28, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Konstantinos FeidantsisBasile Michaelidis
Nov 29, 2011·Marine Environmental Research·Vasileios K DimitriadisBasile Michaelidis
Nov 26, 2010·Marine Environmental Research·D Ezgeta-BalićG Sarà
Oct 13, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Maria KatsikatsouBasile Michaelidis
Jan 5, 2010·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Andreas AnestisBasile Michaelidis
Jun 19, 2009·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Basile MichaelidisAntigone Lazou
Jun 1, 2012·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Konstantinos FeidantsisBasile Michaelidis
Apr 17, 2020·Cell Stress & Chaperones·Andrey Victorovich BorodaNelly Adolphovna Odintsova
Jul 2, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Konstantinos FeidantsisBasile Michaelidis
Feb 15, 2020·Marine Environmental Research·Christina L CollinsMackenzie L Zippay

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