Metabolic Changes and Diabetes Microvascular Complications 5 Years After Obesity Surgery

Obesity Surgery
A D MirasHarvinder S Chahal

Abstract

Obesity surgery has pronounced effects on metabolic profile of patients with type 2 diabetes mellitus (T2DM); however, reports on long-term remission rates based on the standardised and holistic criteria by the International Diabetes Federation (IDF) and effects on T2DM microvascular complications are scarce in the literature. In this retrospective clinical trial, our objectives were to assess these variables 5 years after surgery. Clinical data and direct measurements of renal and retinal damage were collected prospectively and analysed retrospectively for 82 patients with T2DM who underwent obesity surgery and were followed up for 5 years. The cohort of 82 patients with T2DM that were followed up 5 years after obesity surgery was predominantly female (71%) with a median age of 51 years, weight of 133.5 kg, BMI of 46.8 kg/m2 and pre-operative duration of T2DM of 8 years; 6% of patients had diet-controlled T2DM, 57% were on non-insulin treatment and 37% were on insulin treatment pre-operatively. Of the total 82 patients, 59 patients underwent Roux-en-Y gastric bypass, 15 sleeve gastrectomy and 8 patients underwent gastric band operations. At 5 years, 5% and 15% patients achieved optimisation and improvement of the metabolic sta...Continue Reading

References

Sep 18, 2003·Ophthalmology·C P WilkinsonUNKNOWN Global Diabetic Retinopathy Project Group
Oct 31, 2009·Diabetes Care·John B BuseM Sue Kirkman
Apr 13, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·J B DixonUNKNOWN International Diabetes Federation Taskforce on Epidemiology and Prevention
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Jun 11, 2014·JAMA : the Journal of the American Medical Association·Lars SjöströmLena M S Carlsson
Feb 16, 2017·The New England Journal of Medicine·Philip R SchauerUNKNOWN STAMPEDE Investigators

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Citations

Feb 20, 2020·Current Opinion in Endocrinology, Diabetes, and Obesity·Masha G SavelieffEva L Feldman
Aug 28, 2021·Journal of Clinical Medicine·Ana Maria DascaluCatalin Gabriel Smarandache
Sep 23, 2021·International Angiology : a Journal of the International Union of Angiology·Giacomo GastaldiMarie Josee VAN Rijn

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