Metabolic disturbances in patients with cerebral palsy and gastrointestinal disorders

Clinical Nutrition ESPEN
Catalina JaramilloTetyana L Vasylyeva

Abstract

Under nutrition and growth failure are common findings in children with cerebral palsy (CP) and neurologically impairments. Electrolyte and micronutrient abnormalities have also been documented. Gastrointestinal (GI) diseases like gastro esophageal reflux disease (GERD), feeding difficulties and constipation have been associated with increased frequency of these derangements. The goal of this study was to determine the prevalence of malnutrition, metabolic and electrolyte abnormalities in pediatric patients with cerebral palsy and gastrointestinal disorders. A retrospective review of 172 medical records was performed out of which 45 subjects did not have any GI problem, 69 patients had constipation and 58 patients either had GERD, esophagitis, gastrostomy and feeding difficulties. Data collected included: weight, length and body mass index, pre-albumin, albumin, vitamin D, potassium, chloride, bicarbonate, calcium, magnesium (Mg), phosphorus. The results demonstrate a significant difference (p = 0.0126) in the values of albumin in children with CP with GI disorders vs. those without. Additionally, a significant difference (p = 0.0129) was found in Mg levels between CP children with constipation vs. GERD/esophagitis/feeding issu...Continue Reading

References

Jul 5, 2006·Journal of Pediatric Gastroenterology and Nutrition·Valerie MarchandUNKNOWN NASPGHAN Committee on Nutrition

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Citations

Jul 23, 2019·Developmental Medicine and Child Neurology·Renée SpeyerSarah Wilkes-Gillan

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