Metabolic effects of beta 2-agonists
Catecholamines produce a number of biochemical changes most of which result from stimulation of beta 2-receptors. Interest in these metabolic effects has increased recently as a consequence of the concern over the relatively high mortality from acute asthma attacks. In this review the data on the impact of beta 2-agonists on glucose production, insulin release and lipolysis are presented. Thereafter the subject of hypokalaemia, the mechanism for its production by beta 2-agonists and its relevance to cardiac arrhythmias are considered in detail. Finally the fall in plasma magnesium and the possible role of beta 2-agonists in the production of lactic acidosis are discussed.
Haemodynamic effects and pharmacokinetics of a new selective beta1-adrenoceptor agonist, prenalterol, and its interaction with metoprolol in man
Comparison of hormonal and metabolic effects of salbutamol infusion in normal subjects and insulin-requiring diabetics
Differences in metabolic responses to beta-adrenergic stimulation after propranolol or metoprolol administration
Combined effects of adrenaline and insulin on active electrogenic Na+-K+ transport in rat soleus muscle
The immediate effect of a beta-adrenergic agonist (salbutamol) on carbohydrate and lipid metabolism during the third trimester of pregnancy
Assessment of beta-1 selectivity of bisoprolol and atenolol by means of their influence on the lipolytic response to an infusion of terbutaline
Differential effects of beta-adrenergic agonists on insulin secretion from pancreatic islets isolated from rat and man
Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma
Electrocardiographic changes induced by inhaled salbutamol after treatment with bendrofluazide: effects of replacement therapy with potassium, magnesium and triamterene
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene
Intracoronary injections of salbutamol demonstrate the presence of functional beta 2-adrenoceptors in the human heart
Salbutamol induced hypokalaemia: the effect of theophylline alone and in combination with adrenaline
Differences between acute and long-term metabolic and endocrine effects of oral beta-adrenoceptor agonist therapy with pirbuterol for cardiac failure
Metabolic and cardiovascular side effects of the beta 2-adrenoceptor agonists salbutamol and rimiterol
Beta blockade and diabetes mellitus: effect of oxprenolol and metoprolol on the metabolic, cardiovascular, and hormonal response to insulin-induced hypoglycemia in normal subjects
Beta 2-adrenoceptors mediate the stimulating effect of adrenaline on active electrogenic Na-K-transport in rat soleus muscle
Development of tolerance to oral salbutamol in the third trimester of pregnancy: a study of circulatory and metabolic effects
The effects of cardioselective and non-selective beta-adrenoceptor blockade on the hypokalaemic and cardiovascular responses to adrenomedullary hormones in man
Airway and metabolic responsiveness to intravenous salbutamol in asthma: effect of regular inhaled salbutamol
Effects of therapeutic doses of albuterol on beta2-adrenergic receptor density and metabolic changes
Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy
Inhaled Albuterol Use and Impaired Lactate Clearance in Patients With Sepsis: A Retrospective Cohort Study.
Cardiovascular safety of beta(2)-adrenoceptor agonist use in patients with obstructive airway disease: a systematic review
Metabolic acidosis as an underlying mechanism of respiratory distress in children with severe acute asthma
Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. II: long-acting beta-2 agonism
Pilot study to compare the bronchodilator and metabolic responses to terbutaline infusion in seven asthmatic subjects--are they correlated?
Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry
Vasopressors and intestinal mucosal perfusion after cardiac surgery: Norepinephrine vs. phenylephrine
Acid-Base Disturbances in Patients with Asthma: A Literature Review and Comments on Their Pathophysiology
Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia: Systematic Review and Meta-Analysis
Fat metabolism and its response to infusion of insulin and glucose in patients with advanced chronic obstructive pulmonary disease
Lessons of the month 1: Salbutamol induced lactic acidosis: clinically recognised but often forgotten.
Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.
Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.
This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.
Adrenergic Receptors: Trafficking
Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.
Allergy and Asthma
Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.