PMID: 12441985Nov 21, 2002

Metabolic evaluation of children with urolithiasis: are adult references for supersaturation appropriate?

The Journal of Urology
Benjamin S BattinoEugene Minevich

Abstract

We determined the incidence of urinary stone risk factors in pediatric patients with urolithiasis. Between 1998 and 2001, 71 children with urolithiasis at 2 pediatric institutions underwent metabolic evaluation. The 24-hour urine samples were analyzed outside central laboratory using adult and known pediatric references. Supersaturation and traditional metabolic parameters were determined and compared. All patients had metabolic abnormalities. Calcium related abnormalities were present in 92% of children, calcium oxalate supersaturation was abnormal in 69%, calcium phosphate supersaturation was elevated in 70% and traditional calcium parameters were abnormal in 80%. While 11% of the patients had abnormal calcium phosphate or oxalate supersaturation with normal traditional calcium parameters, 10% had normal calcium oxalate or phosphate supersaturation with abnormal traditional calcium parameters. Low urinary volume was identified in 75% of the children. Metabolic abnormalities are extremely common in pediatric patients with urolithiasis. Calcium related abnormalities are the most common abnormality. Urinary supersaturation values are complementary to traditional metabolic parameters and may be more sensitive predictors of recurr...Continue Reading

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Citations

Feb 9, 2007·Pediatric Surgery International·Jallouli MohamedNouri Abdellatif
Feb 18, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Marc B LandeGeorge J Schwartz
Dec 24, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Bernd Hoppe, Markus J Kemper
Apr 1, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Przemysław SikoraBernd Hoppe
Apr 8, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tadeusz PorowskiAgata Korzeniecka-Kozerska
Dec 6, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Concepción Sáez-TorresGuillem Frontera
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Aug 21, 2013·Journal of Pediatric Urology·Jan K KirejczykWojciech Debek
Apr 25, 2008·The Journal of Urology·William DeFoorJ Asplin
Feb 5, 2013·Journal of Pediatric Urology·Nicol Corbin BushKhashayar Sakhaee
Nov 9, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Elżbieta Kuroczycka-SaniutyczAnna Wasilewska
Aug 18, 2004·The Urologic Clinics of North America·Sharon M Bartosh
Sep 2, 2006·The Journal of Urology·William DeFoorEugene Minevich
Nov 17, 2007·The Journal of Urology·Kristy M BorawskiThomas F Kolon
Apr 8, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Vidar O EdvardssonOlafur S Indridason
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Related Concepts

Calcium phosphate
Bio-Base
Monetite
Tetracalcium Phosphate
Calcium phosphate, monobasic, anhydrous
Calcium Oxalate (1: 1)
Calcium Phosphates
Oxalic Acids
Urate
Urinary Calculi

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