Metabolic factors in the causation of urinary tract stones in patients with enterocystoplasties

Urological Research
W G Robertson, C R J Woodhouse

Abstract

Stones are a common complication of the storage of urine in intestinal reservoirs. Previous studies have identified predisposing physical characteristics in the reservoirs. Biochemical and dietary factors have been little investigated. Fifteen patients (6 males and 9 females) who had undergone various enterocystoplasty operations and who had subsequently formed either upper or lower urinary tract stones were investigated. The programme has been previously described and included stone, blood and urine analysis and dietary review. Comparison was made with 15 age- and sex-matched idiopathic stone formers with normal bladders. Stones were infective in origin in 86% of cases, and 14% were sterile. Metabolic screen showed that 80% of enterocystoplasty patients had risk factors for at least three different types of stone. All patients had raised pH (mean 6.93) and hypocitraturia. Five had a raised alkaline phosphatase. Raised serum and urinary calcium, hyperoxaluria and hyperuricosuria were found in 33% of patients. Five had a 24-h urine volume below 1.6 l/day. All patients had a high risk index (PSF) for phosphatic stones and 12 also for calcium oxalate stones. Compared to age-and sex-matched idiopathic stone-formers, the urine had a...Continue Reading

References

May 1, 1977·The Journal of Urology·J G GregoryH W Schoenberg
Jan 1, 1990·Urological Research·W G Robertson
Jun 1, 1986·The Journal of Urology·W S McDougal, M O Koch
Apr 1, 1994·Biochemical Medicine and Metabolic Biology·B Ioannoni, A H Chalmers
Aug 1, 1993·The Journal of Urology·L S PalmerS B Levitt
May 1, 1996·British Journal of Urology·D E NurseA R Mundy
Jun 27, 1998·European Urology·R J BroughD C Gough
Aug 27, 1998·The Journal of Urology·K M KronnerR C Rink
Feb 18, 1999·The Journal of Urology·J J SobleS B Streem
May 3, 2000·BJU International·U BarrosoR González
Aug 25, 2000·The Journal of Urology·M P LeonardP E Williot
Aug 30, 2000·Urology·R B MathoeraR J Nijman
Nov 30, 2000·Scandinavian Journal of Urology and Nephrology·P J OstherK Steven
Mar 29, 2001·European Urology·C R Woodhouse, G N Lennon
Feb 11, 2003·The Journal of Urology·Stephen MadersbacherUrs E Studer
Mar 5, 2003·BJU International·E W GerharzC R J Woodhouse
Sep 6, 2003·Frontiers in Bioscience : a Journal and Virtual Library·William G Robertson
Sep 23, 2003·The Journal of Urology·Willam DeFoorCurtis Sheldon
Oct 21, 2003·Aktuelle Urologie·E W GerharzC R J Woodhouse
Mar 18, 2006·Nephron. Clinical Practice·Aki Hirayama, Sohji Nagase

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Citations

Oct 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·C R J Woodhouse
Nov 27, 2008·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F BruyereE Lechevallier
Oct 13, 2015·Journal of Pediatric Urology·Konrad M SzymanskiMark P Cain
Feb 27, 2018·Current Urology Reports·Melissa R Kaufman
Oct 5, 2010·British Dental Journal·V A C PaulaR Gleiser
Jul 26, 2019·Current Urology Reports·Jeffrey BudzynHumphrey Atiemo

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