Metabolic investigations in patients with hepatitis B and C.

World Journal of Gastroenterology : WJG
Abdul Aziz MastoiWaqas Sami

Abstract

To investigate the similarities and dissimilarities in patients with hepatitis B and hepatitis C, clinically and metabolically. Fifty patients with hepatitis B virus and hepatitis C virus infection were included in this study, along with fifty healthy controls for comparison purposes. Intravenous blood (10 mL) samples from patients and healthy subjects were collected and made to clot before serum was separated and immediately levels of the enzymes, alkaline phosphatase (ALK), creatinine phosphokinase (CPK), lactate dehydrogenase (LDH), serum glutamate oxaloacetate transaminase (s-GOT) and serum glutamate pyruvate transaminase (s-GPT) were determined by a kit method. For total content of each metal the serum samples were analyzed using atomic absorption spectrophotometry. Levels of cholesterol, triglycerides, urea, creatinine and uric acid were determined using a kit method on Microlab 300. Serum magnesium and copper levels remained unchanged, whereas the concentration of zinc decreased and iron increased significantly in both groups of patients. Total antioxidant activity was significantly decreased in both hepatitis B and C. Among the enzymes analyzed, ALK, s-GPT, LDH and s-GOT were all significantly increased in both patients...Continue Reading

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Citations

Sep 8, 2011·Biological Trace Element Research·Naseem RaufShoukat Parvez
Jan 25, 2012·International Journal of Telemedicine and Applications·Mathew J GregoskiFrank A Treiber
Jul 28, 2011·Virology Journal·Eman I ElhawaryMohamed Abdel-Hamid
May 23, 2012·World Journal of Gastroenterology : WJG·Farahnaz JoukarPanah Meskinkhoda
Sep 26, 2015·Lipids in Health and Disease·Sadia Qamar ArainNaseem Aslam Channa
Apr 22, 2015·Mediators of Inflammation·Qiao YangZhi Chen
Mar 3, 2017·Lipids in Health and Disease·Sadia Qamar ArainHassan Imran Afridi
Dec 18, 2020·Applied Spectroscopy·Kamila KochanBayden R Wood

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