Metabolic models of ruminant metabolism: recent improvements and current status

Journal of Dairy Science
M D HaniganJ P McNamara

Abstract

The NC-1009 regional research project has two broad goals of quantifying the properties of feeds and the metabolic interactions among nutrients that influence nutrient availability for milk production and that alter synthesis of milk, and using those quantitative relationships to challenge and refine computer-based nutrition systems for dairy cattle. The objective of this paper was to review progress in modeling. Significant progress has been made in model refinements over the past 10 yr as exemplified by the most recent NRC model (2001) and work on the Molly model of Baldwin and colleagues (1987). These models have different objectives but share many properties. The level of aggregation of the NRC model (2001) does not allow detailed analyses of specific metabolic reactions that affect nutritional efficiency. The Baldwin model is aggregated at the pathway level and is therefore amenable to assessment with a broad range of biological measurements. Recent improvements to that model include the addition of an ingredient based input scheme, use of in situ data to set ruminal protein degradation rates, and refinement of the representation of mammary cell numbers and activity. Although the Baldwin model appears to be appropriate str...Continue Reading

References

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Citations

Jul 1, 2010·Animal : an International Journal of Animal Bioscience·J J Loor
May 20, 2008·Journal of Dairy Science·P C BeukesM E Wastney
Oct 18, 2007·Journal of Animal Science·H A JohnsonR L Baldwin
Oct 13, 2020·Journal of Dairy Science·Meng M Li, Mark D Hanigan

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