Metabolic Network Constrains Gene Regulation of C4 Photosynthesis: The Case of Maize

Plant & Cell Physiology
Semidán Robaina-Estévez, Zoran Nikoloski

Abstract

Engineering C3 plants to increase their efficiency of carbon fixation as well as of nitrogen and water use simultaneously may be facilitated by understanding the mechanisms that underpin the C4 syndrome. Existing experimental studies have indicated that the emergence of the C4 syndrome requires co-ordination between several levels of cellular organization, from gene regulation to metabolism, across two co-operating cell systems-mesophyll and bundle sheath cells. Yet, determining the extent to which the structure of the C4 plant metabolic network may constrain gene expression remains unclear, although it will provide an important consideration in engineering C4 photosynthesis in C3 plants. Here, we utilize flux coupling analysis with the second-generation maize metabolic models to investigate the correspondence between metabolic network structure and transcriptomic phenotypes along the maize leaf gradient. The examined scenarios with publically available data from independent experiments indicate that the transcriptomic programs of the two cell types are co-ordinated, quantitatively and qualitatively, due to the presence of coupled metabolic reactions in specific metabolic pathways. Taken together, our study demonstrates that pr...Continue Reading

References

Jan 14, 2004·Genome Research·Anthony P BurgardCostas D Maranas
Sep 21, 2004·Annual Review of Plant Biology·Gerald E EdwardsElena V Voznesenskaya
Oct 26, 2005·Photosynthesis Research·Marshall D Hatch
Jan 30, 2008·PLoS Computational Biology·Richard A NotebaartBalázs Papp
Mar 28, 2009·Proceedings. Biological Sciences·Andrew D B Leakey
Apr 21, 2010·Trends in Plant Science·Hermann BauweAlisdair R Fernie
Oct 14, 2010·Plant Physiology·Udo Gowik, Peter Westhoff
Oct 27, 2010·Plant Physiology·Cristiana Gomes de Oliveira Dal'MolinLars Keld Nielsen
Nov 3, 2010·Nature Genetics·Pinghua LiThomas P Brutnell
Sep 3, 2011·Nature Protocols·Jan SchellenbergerBernhard Ø Palsson
Jan 21, 2012·Current Opinion in Biotechnology·Sarit Weissmann, Thomas P Brutnell
Mar 13, 2012·Annual Review of Plant Biology·Rowan F SageFerit Kocacinar
Apr 25, 2012·BMC Bioinformatics·Abdelhalim LarhlimiAlexander Bockmayr
Jun 30, 2012·Science·Susanne von CaemmererRobert T Furbank
Mar 29, 2014·Plant Physiology·Christopher R JohnJulian M Hibberd
Jun 14, 2014·Proceedings of the National Academy of Sciences of the United States of America·Samuel M D SeaverChristopher S Henry
Oct 13, 2014·Nature Biotechnology·Lin WangThomas P Brutnell
Jan 22, 2015·Nucleic Acids Research·Matthew E RitchieGordon K Smyth
Mar 26, 2015·Frontiers in Plant Science·Samuel M D SeaverChristopher S Henry
Sep 24, 2015·Plant Physiology·Zoran NikoloskiLee J Sweetlove

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Citations

Jun 5, 2016·Plant & Cell Physiology·Mitsutaka TaniguchiSusanne von Caemmerer
Apr 21, 2020·PLoS Computational Biology·Semidán Robaina-Estévez, Zoran Nikoloski
Jul 14, 2019·Trends in Plant Science·Amy Marshall-Colón, Daniel J Kliebenstein

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