PMID: 5911533Mar 1, 1966

Metabolic properties of histones from rat liver and thymus gland

The Biochemical Journal
M G Ord, L A Stocken

Abstract

1. The incorporation of (14)C-labelled amino acids into acid-extractable proteins from rat-liver and -thymus nuclei confirmed the existence of a protein component with a higher uptake than that into the major histone components. 2. This rapidly labelled component appeared to contain the thiol groups detectable in the acid extracts. 3. Histone f1 contained 1mol. of serine phosphate/mol. of mol.wt. of 42000-43000. 4. Phosphate was present in other components of the 50mm-hydrochloric acid extract from liver and thymus nuclei, and was probably associated with the thiol-containing component. 5. The difference in amino acid uptake into the histones of diffuse and dense chromatin was confirmed. Dense chromatin was found to have a higher proportion of disulphide than did diffuse chromatin.

Citations

Aug 30, 2008·Biochimica Et Biophysica Acta·Ronen Marmorstein, Raymond C Trievel
Apr 22, 2014·Biochimica Et Biophysica Acta·Anna Sawicka, Christian Seiser
Jul 1, 1968·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J G GeorgatsosA Symeonidis
Nov 1, 1973·CRC Critical Reviews in Toxicology·J B Cavanagh
Jan 1, 1986·CRC Critical Reviews in Biochemistry·R S WuW M Bonner
Mar 31, 2006·Proceedings of the National Academy of Sciences of the United States of America·Sandra B Hake, C David Allis
Sep 5, 1973·Biochemical and Biophysical Research Communications·J A Smith, L A Stocken
Nov 10, 1970·Biochemistry·D SherodR Chalkley
Nov 1, 1969·Archives of Biochemistry and Biophysics·J Mohberg, H P Rusch
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Jan 9, 2014·Cancer Metastasis Reviews·Deanna Dryhurst, Juan Ausió
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Sep 14, 2007·Scandinavian Journal of Occupational Therapy·Ann-Britt Ivarsson, Maria Müllersdorf
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Nov 24, 2012·Biopolymers·Robert J Fick, Raymond C Trievel

Related Concepts

Adenine
Cell Nucleus
Chromosomes
Electrophoresis
Histone H7
Liver
Orthophosphate
Thymus Gland

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