PMID: 9422586Jan 9, 1998Paper

Metabolic roles of a Rhodobacter sphaeroides member of the sigma32 family

Journal of Bacteriology
R K KarlsT J Donohue

Abstract

We report the role of a gene (rpoH) from the facultative phototroph Rhodobacter sphaeroides that encodes a protein (sigma37) similar to Escherichia coli sigma32 and other members of the heat shock family of eubacterial sigma factors. R. sphaeroides sigma37 controls genes that function during environmental stress, since an R. sphaeroides deltaRpoH mutant is approximately 30-fold more sensitive to the toxic oxyanion tellurite than wild-type cells. However, the deltaRpoH mutant lacks several phenotypes characteristic of E. coli cells lacking sigma32. For example, an R. sphaeroides deltaRpoH mutant is not generally defective in phage morphogenesis, since it plates the lytic virus RS1, as well as its wild-type parent. In characterizing the response of R. sphaeroides to heat, we found that its growth temperature profile is different when cells generate energy by aerobic respiration, anaerobic respiration, or photosynthesis. However, growth of the deltaRpoH mutant is comparable to that of a wild-type strain under each of these conditions. The deltaRpoH mutant mounted a heat shock response when aerobically grown cells were shifted from 30 to 42 degrees C, but it exhibited altered induction kinetics of approximately 120-, 85-, 75-, and ...Continue Reading

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Citations

Aug 4, 2006·Journal of Bacteriology·Heather A Green, Timothy J Donohue
Nov 3, 2009·Nature Reviews. Microbiology·Eva C Ziegelhoffer, Timothy J Donohue
Mar 2, 2002·Journal of Bacteriology·Ran RosenEliora Z Ron
Jan 21, 2003·Mass Spectrometry Reviews·Ran Rosen, Eliora Z Ron
Dec 5, 2017·Microbes and Environments·Hisayuki Mitsui, Kiwamu Minamisawa
May 22, 2019·Molecular Microbiology·Timothy J Donohue

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