PMID: 6108235Mar 1, 1980Paper

Metabolic shifts during the repeated administration of analeptics in alcoholic intoxication

Farmakologiia i toksikologiia
K I BenderV V Kupchikov

Abstract

It was shown in experiments on rabbits that under acute alcohol poisoning of medium degree, repeated administration of caffeine (10 mg/kg) and bemegrid in particular (5 mg/kg) promotes aerobization of the oxidative processes and mobilizes the respiratory mechanism of metabolic acidosis compensation. Under these conditions, ethimizol (10 mg/kg) stimulates the respiratory center and promotes (to a less measure) aerobization of the metabolic processes in tissues and ethanol elimination.

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