Metabolic support of the enterocutaneous fistula patient

Clinics in Colon and Rectal Surgery
Joshua I S Bleier, Traci Hedrick

Abstract

Enterocutaneous fistula (ECF) is a challenging clinical problem with many etiologies; however, the most common cause is iatrogenic, complicating abdominal surgery. Advances in the overall care of the ECF patient have resulted in dramatic reductions in morbidity and mortality over the last five decades. A structured approach to the management of ECF has been shown to result in improved outcomes. Initial physiologic stabilization of the postoperative patient, focused on hemodynamic and fluid support as well as aggressive sepsis control are the critical initial maneuvers. Subsequent optimization of nutrition and wound care allows the patient to regain a positive nitrogen balance, and allow for healing. Judicious use of antimotility agents as well as advanced wound care techniques helps to maximize healing as well as quality of life, and prepare patients for subsequent definitive surgery.

References

May 5, 1999·World Journal of Surgery·Stanley J DudrickA A McKelvey
Apr 29, 2000·World Journal of Surgery·C AlvarezH A Reber
Aug 31, 2001·JAMA : the Journal of the American Medical Association·D K HeylandU Suchner
Aug 2, 2002·Postgraduate Medical Journal·C CroK R Gardiner
Aug 1, 1964·American Journal of Surgery·R CHAPMANJ E DUNPHY
Jun 29, 2006·The British Journal of Surgery·D A J LloydA C J Windsor
Oct 3, 2006·Surgery·John M DrausGerald M Larson
Nov 7, 2006·Surgical Infections·Traci L HedrickRobert G Sawyer
Nov 24, 2006·Annals of Plastic Surgery·Laura A GunnDetlev Erdmann
Jan 2, 2007·Journal of Clinical Gastroenterology·Alexandre R MarraDonald F Kirby
Sep 28, 2007·World Journal of Surgery·Daniel Edgardo WainsteinDario Berkowski
Dec 26, 2007·Critical Care Medicine·R Phillip DellingerWorld Federation of Societies of Intensive and Critical Care Medicine
Jan 5, 2008·World Journal of Surgery·R G J VisschersW G van Gemert
Jul 4, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·James D PaauwAlan T Davis
Jul 16, 2008·Intensive Care Medicine·Paul E Marik, Gary P Zaloga
Sep 3, 2008·The British Journal of Surgery·R G J VisschersW G van Gemert
Feb 14, 2009·The American Surgeon·Pedro G R TeixeiraDemetrios Demetriades
Mar 31, 2009·Current Problems in Surgery·Myles R Joyce, David W Dietz
May 7, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·M Isabel FielThomas D Schiano
Oct 6, 2009·Journal of the American College of Surgeons·William P SchecterStanley J Dudrick
Dec 26, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph S SolomkinJohn G Bartlett

Citations

May 1, 2012·European Radiology·Liana Cambj SapunarNikica Družijanić
Oct 29, 2011·World Journal of Surgery·Travis M Polk, C William Schwab
Dec 3, 2014·Journal of Vascular and Interventional Radiology : JVIR·Feraz N Rahman, Joseph M Stavas
Jul 10, 2019·Diseases of the Colon and Rectum·Anuradha R Bhama
Dec 29, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Caroline CouperEzra Steiger

Related Concepts

Hemodynamics
Nitrogen
Wound Healing
Operation on Abdominal Region
Enterocutaneous Fistula
Disease Management
Operative Surgical Procedures
Wound Care
Pharmacologic Substance
Aggressive Cancer

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