Metabolic Syndrome and Abnormal Peri-Organ or Intra-Organ Fat (APIFat) Deposition in Chronic Obstructive Pulmonary Disease: An Overview

Metabolites
Niki KatsikiDimitri P Mikhailidis

Abstract

Chronic obstructive pulmonary disease (COPD) is a common disorder with an increasing prevalence, characterised by persistent respiratory symptoms and airflow limitation. Systemic inflammation is involved in the pathogenesis of COPD and can also predispose to metabolic disorders (e.g., metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD)). Such comorbidities can negatively affect COPD outcomes, cardiovascular risk, and quality of life. Apart from NAFLD, abnormal peri-organ or intra-organ fat (APIFat) could be considered as markers for cardiometabolic diseases and even for COPD. The present narrative review considers the associations of COPD with MetS, NAFLD, and other APIFat, including epicardial, perirenal, peripancreatic, and intramuscular adipose tissue. Further research is needed to define these relationships and identify any potential clinical implications.

References

Jul 27, 2000·The New England Journal of Medicine·P J Barnes
Mar 5, 2004·The New England Journal of Medicine·Bartolome R CelliHoward J Cabral
Aug 2, 2005·Journal of Cardiopulmonary Rehabilitation·Karine MarquisPaul Poirier
Aug 26, 2006·Nature Clinical Practice. Endocrinology & Metabolism·Aoife M Brennan, Christos S Mantzoros
Sep 20, 2007·Proceedings of the American Thoracic Society·Alvar Agustí
Apr 17, 2008·COPD·Alvar Agusti, Joan B Soriano
Jun 27, 2008·The European Respiratory Journal·D M ManninoF Holguin
Jan 13, 2009·American Journal of Respiratory and Critical Care Medicine·Nathalie LeoneMahmoud Zureik
Nov 21, 2009·Journal of Applied Physiology·Akshay Sood
Aug 7, 2010·Physical Therapy·Stephanie L Di StasiStuart A Binder-Macleod
Nov 3, 2010·Journal of Cardiopulmonary Rehabilitation and Prevention·Marc RoigWendy D Reid
Jan 7, 2011·Chest·Yvonne Nussbaumer-Ochsner, Klaus F Rabe
Jan 26, 2011·Expert Opinion on Therapeutic Targets·Niki KatsikiDimitrios Karamitsos
Mar 25, 2011·Therapeutic Advances in Respiratory Disease·Alice Huertas, Paolo Palange
Apr 12, 2011·Current Opinion in Cardiology·Niki KatsikiDimitri P Mikhailidis
Oct 4, 2011·Internal and Emergency Medicine·Enrico CliniMario Malerba
Dec 21, 2011·Internal Medicine Journal·D-H JungY-J Lee
Jun 26, 2012·International Journal of Cardiology·Stefania MarianiLucio Gnessi
Feb 2, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·Octavian C Ioachimescu, Mihaela Teodorescu
Feb 8, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·G MussoR Gambino
Mar 5, 2013·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Stephan F van Eeden, Don D Sin
Apr 18, 2013·Current Opinion in Cardiology·Niki KatsikiAnthony S Wierzbicki
May 1, 2013·Current Vascular Pharmacology·Niki KatsikiDimitri P Mikhailidis
May 7, 2013·Internal and Emergency Medicine·Jesús Díez-ManglanoUNKNOWN Working Group on COPD; Spanish Society of Internal Medicine
Jun 13, 2013·JAMA : the Journal of the American Medical Association·Mette ThomsenBørge G Nordestgaard
Jun 14, 2013·PloS One·Jorge ZagacetaJuan P de Torres
Jul 6, 2013·The International Journal of Biochemistry & Cell Biology·R C J LangenA M W J Schols
Sep 18, 2013·Current Pharmaceutical Design·Niki KatsikiDimitri P Mikhailidis
Dec 3, 2013·Western Journal of Nursing Research·Soo Kyung Park, Janet L Larson
Dec 11, 2013·Current Pharmaceutical Design·Niki KatsikiDimitri P Mikhailidis
Jan 1, 2014·European Journal of Clinical Investigation·Chiara RossiAnna Solini
Feb 28, 2014·Journal of the American Heart Association·Chih-Yuan WangChih-Jen Chang
Jun 3, 2014·The Journal of Nutrition, Health & Aging·O AddisonR L Marcus
Jul 6, 2014·The European Respiratory Journal·Matthew MaddocksNicholas S Hopkinson
Jul 17, 2014·Current Opinion in Cardiology·Niki KatsikiDimitri P Mikhailidis
Nov 7, 2014·Medicine and Science in Sports and Exercise·Priscila Games RoblesSunita Mathur

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