Metabolic syndrome and metabolic risk profile according to polycystic ovary syndrome phenotype

The Journal of Obstetrics and Gynaecology Research
Enes BilSerdar Dilbaz

Abstract

It is unknown which phenotype of polycystic ovary syndrome (PCOS) has a greater metabolic risk and how to detect this risk. The aim of this study was therefore to compare the incidence of metabolic syndrome (MetS) and metabolic risk profile (MRP) for different phenotypes. A total of 100 consecutive newly diagnosed PCOS women in a tertiary referral hospital were recruited. Patients were classified into four phenotypes according to the Rotterdam criteria, on the presence of at least two of the three criteria hyperandrogenism (H), oligo/anovulation (O) and PCO appearance (P): phenotype A, H + O + P; phenotype B, H + O; phenotype C, H + P; phenotype D, O + P. Prevalence of MetS and MRP were compared among the four groups. Based on Natural Cholesterol Education Program Adult Treatment Panel III diagnostic criteria, MetS prevalence was higher in phenotypes A and B (29.6% and 34.5%) compared with the other phenotypes (10.0% and 8.3%; P < 0.001). Although the prevalence of obesity was similar, the number of patients with homeostatic model assessment insulin resistance index (HOMA-IR) >3.8 was significantly higher in androgenic PCOS phenotypes. After logistic regression analysis, visceral adiposity index (VAI) was the only independent p...Continue Reading

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Citations

Feb 1, 2017·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Fatih CelikMine Kanat Pektas
May 31, 2018·Endocrine Connections·Katica Bajuk Studen, Marija Pfeifer
Jul 6, 2020·Immunity, Inflammation and Disease·Nahid LorzadehYasaman Kazemirad
Apr 7, 2019·Reproductive Biology and Endocrinology : RB&E·Pernille Bækgaard UdesenLouise Torp Dalgaard
Nov 18, 2020·Archives of Gynecology and Obstetrics·Sebastião Freitas de MedeirosGustavo Arantes Rosa Maciel
Jan 15, 2021·Archives of Endocrinology and Metabolism·Sepide Gohari TabanTayebe Artimani
Apr 2, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Zhexin NiChaoqin Yu
May 15, 2021·Diabetes/metabolism Research and Reviews·Anna Krentowska, Irina Kowalska
Sep 18, 2021·The Canadian Journal of Cardiology·Julia SmithNatalie Dayan

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