PMID: 15225497Jul 1, 2004Paper

Metabolic syndrome as a cardiovascular risk factor in patients with type 2 diabetes

Revista española de cardiología
José A Gimeno OrnaDesirée P Portilla Córdoba

Abstract

To assess the cardiovascular risk associated with the presence of metabolic syndrome in patients with type 2 diabetes. Patients and method. Prospective cohort study of patients with type 2 diabetes. The baseline presence of components of metabolic syndrome as defined by the World Health Organization was determined. The main dependent variable was a combination of coronary events (onset angina, fatal or nonfatal myocardial infarction) and cerebrovascular events (transient ischemic attack, fatal or nonfatal stroke and lower limb amputation). Secondary end points were coronary events and stroke. We calculated the predictive power of the presence of metabolic syndrome and of different numbers of its component features. 318 patients were included. Mean duration of follow-up was 4.6 years (SD 1.5 years). The prevalence of metabolic syndrome was 77.0%. The rates of cardiovascular events, coronary events and stroke, expressed per 1000 patient-years, were 14.0, 5.6, and 8.4 respectively in patients without metabolic syndrome, and 33.3, 20.7, and 11.7 respectively in patients with metabolic syndrome (P=.058 cardiovascular events; P=.05 coronary events). In the multivariate analysis, the simultaneous presence of all four metabolic syndrom...Continue Reading

References

Jun 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·E L Bierman
Feb 6, 1991·JAMA : the Journal of the American Medical Association·E L Barrett-ConnorS L Edelstein
Jan 27, 1999·Epidemiologic Reviews·A D LieseS M Haffner
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Dec 4, 2002·JAMA : the Journal of the American Medical Association·Hanna-Maaria LakkaJukka T Salonen
Jan 10, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·K I BirkelandK F Hanssen

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Citations

Apr 9, 2014·European Journal of Internal Medicine·Ana Torres do RegoLuis Antonio Alvarez-Sala Walther
Nov 26, 2015·Diabetology & Metabolic Syndrome·Laura KazlauskienėAntanas Norkus
Sep 27, 2006·The American Journal of Medicine·Andrea GalassiJiang He

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