Metabolic Syndrome May Exacerbate Macular and Retinal Damage in Psoriasis Vulgaris

Ocular Immunology and Inflammation
Selma KorkmazSadık Altan Özal

Abstract

To evaluate whether cases with both psoriasis and metabolic syndrome are prone to retinal and macular changes. A total of 174 eyes of 87 subjects were evaluated. Of the 87 subjects, 24 had psoriasis, 19 had psoriasis and metabolic syndrome, 18 had metabolic syndrome only and 26 were healthy subjects. Biochemical analysis, anthropometric, blood pressure and optical coherence tomography measurements and thickness analysis were obtained for each case. The superior retinal nerve fibre layer thickness was significantly lower in the psoriasis and metabolic syndrome group than in the psoriasis group. For all parafoveal quadrants, the ganglion cell complex thickness was statistically significantly lower in the psoriasis group than in the healthy group. The central macula was thinnest in the healthy group among the four groups. Psoriasis can cause retinal changes, and metabolic syndrome may cause additional damage in the retina and macula in cases with psoriasis.

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Citations

Jul 5, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gözde Sahin, Derya Dal
Dec 9, 2020·International Journal of Clinical Practice·Mustafa AksoyIsa An
Sep 25, 2020·Minerva endocrinologica·Claudio MarascaGiuseppina Fontanella

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