Metabolism of 4-hydroxy-2,3-pentene-1-al in submitochondrial fractions of mouse liver

Chemico-biological Interactions
S F Hakki, J T Nodes

Abstract

The location of the enzymic system involved in the metabolism of 4-hydroxy-2-3-pentene-1-al (HPE) in the livers of female mice (CBA/CA) has been established. All mitochondrial membranes showed some activity with slightly higher metabolism in the matrix. The enzymic system had a pH optimum of 8.8 using pyrophosphate buffer. Suitable marker enzymes were used to test the contamination of the different submitochondrial fractions with each other.

References

Apr 1, 1975·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P J ConroyG W White
Apr 1, 1975·Archives of Biochemistry and Biophysics·A A Horton, M C Barrett
Jul 27, 1975·Biochimica Et Biophysica Acta·T Koivula, M Koivusalo

Citations

Mar 21, 1986·Biochimica Et Biophysica Acta·H EsterbauerM Comporti
Jan 1, 1985·The International Journal of Biochemistry·M F Kenel, A P Kulkarni
Jan 1, 1989·Free Radical Biology & Medicine·G Witz

Related Concepts

Aldehydes
Pentadienes
Metazoa
Hydrogen-Ion Concentration
Intracellular Membranes
Liver
Mitochondria, Liver
Mouse, Swiss

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