Metabolism of conjugated linoleic acids and 18 : 1 fatty acids by ruminal bacteria: products and mechanisms

Microbiology
Nest McKainR John Wallace

Abstract

Cultures of ruminal bacteria known to metabolize unsaturated fatty acids were grown in medium containing 50 microg ml(-1) of geometric and positional isomers of conjugated linoleic acid (CLA) or 18 : 1 fatty acids and 37.4 % deuterium oxide to investigate the mechanisms responsible for fatty acid metabolism. Butyrivibrio fibrisolvens JW11 converted cis-9,trans-11-18 : 2 and trans-9,trans-11-18 : 2 to trans-11-18 : 1 as the main product, labelled at C-9, and metabolized trans-10,cis-12-18 : 2 to trans-10-18 : 1, labelled at C-13, and smaller amounts of trans-12-18 : 1 and cis-12-18 : 1. Butyrivibrio proteoclasticus P-18 did not grow in the presence of cis-9,trans-11-18 : 2 or trans-10,cis-12-18 : 2, but grew in medium containing trans-9,trans-11-18 : 2, forming 18 : 0. Propionibacterium acnes, a ruminal species that isomerizes linoleic acid to trans-10,cis-12-18 : 2, did not metabolize CLA isomers further. B. fibrisolvens metabolized small amounts of trans-10-18 : 1, trans-11-18 : 1 and cis-9-18 : 1, but the products formed were not detected. B. proteoclasticus, on the other hand, carried out substantial conversion of 18 : 1 substrates to 18 : 0. P. acnes hydrated cis-9-18 : 1 and trans-11-18 : 1 to 10-OH-18 : 0, which was furth...Continue Reading

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Citations

Jul 1, 2010·Animal : an International Journal of Animal Bioscience·M LourençoR J Wallace
Jul 1, 2010·Animal : an International Journal of Animal Bioscience·K J ShingfieldY Chilliard
Oct 4, 2012·Animal : an International Journal of Animal Bioscience·K J ShingfieldN D Scollan
Jan 3, 2014·The Journal of Dairy Research·Leacady SalibaP Yvan Chouinard
Sep 25, 2010·Applied Microbiology and Biotechnology·Mamun M Or-RashidBrian W McBride
Jul 26, 2011·Journal of Environmental Management·Joaquin AnguloJorge Gallo
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May 31, 2017·Journal of Applied Microbiology·F EnjalbertA Meynadier
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Nov 21, 2017·Journal of Dairy Science·Mary Beth Hall, David R Mertens
Aug 15, 2017·Journal of Dairy Science·Susana P AlvesRui J B Bessa

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