Metabolism of the Pacific oyster,Crassostrea gigas , is influenced by salinity and modulates survival to the Ostreid herpesvirus OsHV-1

Biology Open
Marine FuhrmannFabrice Pernet

Abstract

The Pacific oyster,Crassostrea gigas, is an osmoconforming bivalve exposed to wide salinity fluctuations. The physiological mechanisms used by oysters to cope with salinity stress are energy demanding and may impair other processes, such as defense against pathogens. This oyster species has been experiencing recurrent mortality events caused by the Ostreid herpesvirus 1 (OsHV-1). The objectives of this study were to investigate the effect of salinity (10, 15, 25 and 35‰) on energetic reserves, key enzyme activities and membrane fatty acids, and to identify the metabolic risk factors related to OsHV-1-induced mortality of oysters. Acclimation to low salinity led to increased water content, protein level, and energetic reserves (carbohydrates and triglycerides) of oysters. The latter was consistent with lower activity of hexokinase, the first enzyme involved in glycolysis, up-regulation of AMP-activated protein kinase, a major regulator of cellular energy metabolism, and lower activity of catalase, an antioxidant enzyme involved in management of reactive oxygen species. Acclimation to salinity also involved a major remodeling of membrane fatty acids. Particularly, 20:4n-6 decreased linearly with decreasing salinity, likely reflec...Continue Reading

References

Jan 1, 1984·Methods in Enzymology·H Aebi
Sep 24, 1982·Science·P H YanceyG N Somero
Jul 15, 1993·European Journal of Biochemistry·H Sies
May 20, 2000·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·C BerthelinM Mathieu
Jun 28, 2002·The Biological Bulletin·Jonathon M HallRaymond J Thompson
Jun 11, 2003·The Journal of Experimental Biology·A J Hulbert
Jul 25, 2003·The Journal of Experimental Biology·Maryse DelaporteJean-François Samain
Dec 12, 2003·Diseases of Aquatic Organisms·H I ReidT H Birkbeck
Sep 17, 2004·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Doris Abele, Susana Puntarulo
Feb 8, 2006·Annual Review of Physiology·Michael P Lesser
Oct 28, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Philip C Calder
Oct 1, 2009·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Myung In An, Cheol Young Choi
Jul 6, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Laura CanesiGabriella Gallo
Jun 1, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Catherine SeguineauPhilippe Soudant
Dec 14, 2011·The Journal of Experimental Biology·Gary H DickinsonInna M Sokolova
Aug 11, 2012·Journal of Proteomics·Charlotte CorporeauStéphanie Madec
Jul 3, 2013·Annual Review of Marine Science·Colleen A BurgeC Drew Harvell
Jul 23, 2013·Journal of Invertebrate Pathology·Philippe SoudantAswani Volety
Oct 17, 2013·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·A J HulbertSarah K Abbott
Feb 22, 2014·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Vanessa CarregosaRosa Freitas
Jul 11, 2014·Journal of Proteomics·Charlotte CorporeauStéphanie Madec
Aug 19, 2014·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Vanessa CarregosaRosa Freitas
Aug 28, 2015·Chemical Research in Toxicology·Yanouk EpelboinCharlotte Corporeau
Feb 28, 2016·Developmental and Comparative Immunology·Gaëlle RichardFabrice Pernet
Apr 21, 2016·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Chang XuLiqiao Chen
Jul 16, 2016·Experimental & Molecular Medicine·Sang-Min Jeon

❮ Previous
Next ❯

Citations

Feb 11, 2020·Frontiers in Physiology·J Kirsikka SillanpääKristina Sundell
Jun 27, 2020·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Anna V IvaninaInna M Sokolova

❮ Previous
Next ❯

Methods Mentioned

BETA
protein assay

Software Mentioned

Wincats
R
SAS
Gen5

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.