Metabolomics applications of FT-ICR mass spectrometry

Mass Spectrometry Reviews
Stephen C BrownJean-Louis Dasseux

Abstract

Metabolomics, also known as Metabolic Profiling, is an emerging discipline under the umbrella concept of systems biology. The goal of metabolomics is to know and understand the concentrations and fluxes of endogenous metabolites within a living biological system under study. General tools are being developed for the rapid measurement of many metabolites in a single experiment, most of which are mass spectrometric methods. FT-ICR has unique advantages, as a mass spectrometric method, in this regard. Applications of FT-ICR to metabolomics analyses will be discussed and reviewed in the context of the single publication currently available.

References

Apr 16, 1998·The Journal of Biological Chemistry·R Eisenthal, A Cornish-Bowden
Sep 1, 1999·European Journal of Biochemistry·E K Ainscow, M D Brand
Nov 4, 2000·Nature Biotechnology·O FiehnL Willmitzer
Apr 3, 2001·Journal of the American Society for Mass Spectrometry·F W McLaffertyB K Carpenter
May 18, 2001·Trends in Biotechnology·M Tomita
Dec 26, 2001·Nucleic Acids Research·Minoru KanehisaAkihiro Nakaya
Dec 26, 2001·Nucleic Acids Research·Ida SchomburgDietmar Schomburg
Mar 5, 2002·Nature Biotechnology·Marta CascantePaul W-N Lee
Sep 6, 2002·Cardiovascular Toxicology·D G RobertsonL A Dethloff
Nov 13, 2002·Omics : a Journal of Integrative Biology·Asaph AharoniDayan B Goodenowe
Feb 13, 2003·European Journal of Biochemistry·Oliver Fiehn, Wolfram Weckwerth
Mar 29, 2003·Toxicology and Applied Pharmacology·John C LindonCraig Thomas
May 29, 2003·The Journal of Nutrition·Robert-Jan A N LamersJoop H J van Nesselrooij

❮ Previous
Next ❯

Citations

Sep 7, 2006·Analytical and Bioanalytical Chemistry·Zhengzheng Pan, Daniel Raftery
Sep 6, 2007·Analytical and Bioanalytical Chemistry·E D RaczyńskaM Szelag
Jan 29, 2013·Analytical and Bioanalytical Chemistry·Constanze MüllerPhilippe Schmitt-Kopplin
Aug 1, 2007·Applied Microbiology and Biotechnology·Marco OldigesChristiane Wiendahl
Oct 13, 2005·Plant Cell Reports·Ritu BhallaSanjay Swarup
Sep 27, 2006·Pituitary·Joseph E Ippolito
Apr 16, 2005·Current Opinion in Biotechnology·Kirsi-Marja Oksman-Caldentey, Kazuki Saito
Jul 15, 2006·Journal of the American Society for Mass Spectrometry·Yehia IbrahimRichard D Smith
Apr 18, 2008·Journal of the American Society for Mass Spectrometry·Haichuan LiuKristina Håkansson
Nov 21, 2007·Nature Reviews. Microbiology·Rainer BreitlingMichael P Barrett
Oct 8, 2005·Omics : a Journal of Integrative Biology·G D StentifordS W Feist
Dec 4, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Donald G RobertsonMichael D Reily
Mar 24, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Julian L Griffin
Feb 16, 2006·BMC Bioinformatics·Christian V ForstPeter F Stadler
Jun 1, 2010·Journal of Toxicologic Pathology·Mina HasegawaShigeo Takenaka
May 19, 2010·Biomarkers in Medicine·G A Nagana GowdaTedros Bezabeh
Nov 9, 2006·Biotechnology Letters·Mlawule R MashegoJoseph J Heijnen
Nov 30, 2010·Journal of Biomedicine & Biotechnology·Young S Kim, John A Milner
Jan 1, 2006·Metabolomics : Official Journal of the Metabolomic Society·Rainer BreitlingMichael P Barrett
Dec 17, 2008·Metabolomics : Official Journal of the Metabolomic Society·Jun HanChristoph H Borchers
Oct 8, 2005·Expert Review of Proteomics·Chun-Ming HuangCraig A Elmets
Sep 13, 2008·Expert Review of Molecular Diagnostics·G A Nagana GowdaDaniel Raftery
Jul 26, 2006·Expert Opinion on Drug Metabolism & Toxicology·Donald G RobertsonJ David Baker
Oct 24, 2015·Archives of Biochemistry and Biophysics·Toby Athersuch
Jan 16, 2015·Mass Spectrometry Reviews·Tiago F JorgeCarla António
Apr 13, 2011·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Hao-Yang WangYin-Long Guo
May 21, 2009·Experimental and Molecular Pathology·Andrew N LaneDonald M Miller
May 18, 2010·International Journal of Mass Spectrometry·Aleksey V TolmachevRichard D Smith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.