Metabolomics to Exploit the Primed Immune System of Tomato Fruit

Metabolites
Estrella LunaPierre Pétriacq

Abstract

Tomato is a major crop suffering substantial yield losses from diseases, as fruit decay at a postharvest level can claim up to 50% of the total production worldwide. Due to the environmental risks of fungicides, there is an increasing interest in exploiting plant immunity through priming, which is an adaptive strategy that improves plant defensive capacity by stimulating induced mechanisms. Broad-spectrum defence priming can be triggered by the compound ß-aminobutyric acid (BABA). In tomato plants, BABA induces resistance against various fungal and bacterial pathogens and different methods of application result in durable protection. Here, we demonstrate that the treatment of tomato plants with BABA resulted in a durable induced resistance in tomato fruit against Botrytiscinerea, Phytophthorainfestans and Pseudomonassyringae. Targeted and untargeted metabolomics were used to investigate the metabolic regulations that underpin the priming of tomato fruit against pathogenic microbes that present different infection strategies. Metabolomic analyses revealed major changes after BABA treatment and after inoculation. Remarkably, primed responses seemed specific to the type of infection, rather than showing a common fingerprint of BAB...Continue Reading

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Methods Mentioned

BETA
PCA
metabolomic profiling
NMR

Software Mentioned

MeV
MarVis
MetaboAnalyst
R
XCMS
Thermo XCalibur
glmnet

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