Metachronous colorectal cancer

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
I J ParkJ C Kim

Abstract

Although the diagnosis of metachronous colorectal cancer have increased, due primarily to improvements in diagnostic modalities, the potential risk factors for these tumours are not well known. We compared the characteristics of patients with metachronous and sporadic primary colorectal cancer to determine risk factors for its occurrence. We reviewed the records of 5447 patients with colorectal cancer, who had been treated at Asan Medical Centre between July 1989 and January 2004. A metachronous cancer was defined as a secondary colorectal cancer occurring more than 6 months after the index cancer. Metachronous colorectal cancer occurred in 39 (0.7%) patients. Their average age was 53 years, somewhat younger than the average age of sporadic colorectal cancer patients (58 years). In patients with metachronous cancer, the cancer was more likely to be located in the right colon (P < 0.03), and the incidence of synchronous polyps or cancer was significantly higher (P < 0.001). The relative distributions of histological grades and clinicopathological characteristics were similar in index and metachronous cancers. Metachronous cancers were diagnosed more frequently at an early stage. The time interval between index and metachronous c...Continue Reading

References

Dec 1, 1975·Cancer·M K Schwartz
Dec 1, 1975·Cancer·T MutoB C Morson
Mar 1, 1990·World Journal of Surgery·G JuhlH C Polk
Jul 1, 1988·Diseases of the Colon and Rectum·B M EversH C Polk
Jun 1, 1986·Diseases of the Colon and Rectum·P J KieferM A Christensen
Mar 1, 1987·Diseases of the Colon and Rectum·M A LuchtefeldJ R Folse
Jan 1, 1972·The British Journal of Surgery·R J Heald, H E Lockhart-Mummery
Jan 1, 1972·Diseases of the Colon and Rectum·C R TraviesoP H Hanley
Dec 1, 1984·The British Journal of Surgery·W J CunliffeP F Schofield
Sep 1, 1982·Diseases of the Colon and Rectum·M V AgrezR W Beart
Apr 1, 1993·Diseases of the Colon and Rectum·R L CaliM A Christensen
Jul 1, 1997·The British Journal of Surgery·S B SenguptaJ D Delhanty
Jun 23, 1999·Diseases of the Colon and Rectum·R L NelsonM Turyk
Dec 10, 1999·The Medical Clinics of North America·J F Helm, R S Sandler
Oct 18, 2000·Annals of Internal Medicine·A SonnenbergJ M Inadomi
Oct 18, 2002·Journal of Cancer Research and Clinical Oncology·Yasushi FukutomiMitsuo Ninomiya
Mar 26, 2003·Journal of Gastroenterology and Hepatology

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Citations

Jul 26, 2012·International Journal of Colorectal Disease·Alfred King-Yin LamSimon Siu
Mar 3, 2011·International Journal of Clinical Oncology·Yoshito IkematsuYoshiro Nishiwaki
Feb 9, 2012·International Journal of Clinical Oncology·Tzu-An ChenWen-Chu Lin
Jul 23, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C L RinglandR L Ward
Jan 8, 2011·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Fatih Safa ErenayRobert R Cima
Apr 1, 2012·Clinical Journal of Gastroenterology·Yoshito IkematsuYoshiro Nishiwaki
Oct 13, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R Nelson
Aug 21, 2012·International Journal of Cancer. Journal International Du Cancer·Fabio LeviCarlo La Vecchia
May 21, 2014·Surgery Today·Toshiya NagasakiToshiharu Yamaguchi
Feb 26, 2016·Oncotarget·Takaharu KatoToshiki Rikiyama
Apr 20, 2012·Diseases of the Colon and Rectum·Sanna A MulderMonique E van Leerdam
Sep 25, 2008·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·H H WasmuthO Røkke
Jun 27, 2019·Gastroenterology Research and Practice·Yeon-Ji KimJi Min Lee
Jan 23, 2021·Scientific Reports·Tatsunori MinamideTomonori Yano

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