Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

BMC Cancer
Taro TanabeYukihide Kanemitsu

Abstract

Inguinal lymph node metastasis from rectum is uncommon but well-known occurrence, whereas that from colon adenocarcinoma is extremely rare. Inguinal lymph node metastasis from colon adenocarcinoma has only been reported in previous cases involving primary tumor invasion of the abdominal wall, or in those involving colon cancer metastasis to external iliac lymph nodes. We describe a case of inguinal lymph node metastasis from colon cancer without primary tumor invasion to the abdominal wall. A 42-year-old female, who had undergone twice cesarean sections before, underwent open sigmoidectomy for sigmoid colon adenocarcinoma and received 12 cycles of FOLFOX regimen as adjuvant chemotherapy. Two years after sigmoidectomy, a follow-up CT scan revealed enlarged inguinal lymph nodes as well as growth of enhanced mass lesions on the abdominal wall at site of the cesarean section scar. Biopsy of both lesions revealed well-differentiated adenocarcinoma, and immunohistochemistry demonstrated positive expression of CDX2, substantiating its gastrointestinal origin. We therefore performed dissection of left inguinal lymph nodes and mass lesion of the abdominal wall. The patient died 51 months after lymph node dissection. This is the first re...Continue Reading

References

May 29, 2000·Diseases of the Colon and Rectum·J B KoeaA M Cohen
Mar 22, 2002·AJR. American Journal of Roentgenology·Thomas Magee, Howard Rosenthal
Aug 1, 1942·Annals of Surgery·R S Grinnell
Oct 18, 2011·World Journal of Surgical Oncology·Adolfo PisanuAlessandro Uccheddu
Jul 10, 2013·International Journal of Colorectal Disease·Tomohiro AdachiHideki Ohdan
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May 11, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S MerkelC Wittekind

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Methods Mentioned

BETA
cesarean sections
dissection
cesarean section
biopsy

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