Metacognition in functional cognitive disorder- a potential mechanism and treatment target

Cognitive Neuropsychiatry
Rohan BhomeRobert J Howard

Abstract

Introduction: Functional Cognitive Disorder (FCD) is common. Despite this, there is no evidence-based consensus on how to treat FCD. Poor metacognitive ability has been suggested as a key mechanism underlying the disorder. This paper evaluates the proposal that strategies which improve metacognition could provide a mechanistically plausible translational therapy. Methods: We reviewed the existing literature relating to metacognition in FCD, previous strategies to improve metacognitive ability in FCD and whether metacognitive performance can be modulated. Results: Though limited, there is evidence to suggest that metacognition is impaired in FCD. Converging evidence from neuroimaging studies suggests that metacognitive performance can be modulated. The effectiveness of existing strategies to improve metacognition including cognitive training, psychoeducation and lifestyle interventions have been equivocal. Recently, a potential treatment option has emerged in the form of a computer-based metacognitive training paradigm. Conclusions: There is an urgent need for effective treatments in FCD. Impaired metacognition may be a plausible therapeutic target but, in the first instance, further research is required to demonstrate deficits ...Continue Reading

References

Sep 1, 1985·Journal of Gerontology·F ScoginL Lott
May 30, 2006·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Gary W SmallMichael E Phelps
May 9, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Dean C Delis, Spencer R Wetter
Nov 29, 2008·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Klaus SchmidtkeBirgitta Metternich
Feb 27, 2009·Psychotherapie, Psychosomatik, medizinische Psychologie·Birgitta MetternichMichael Hüll
Apr 22, 2009·Journal of Psychosomatic Research·Birgitta MetternichMichael Hüll
Aug 19, 2009·Journal of Psychosomatic Research·Klaus Schmidtke, Birgitta Metternich
Sep 18, 2010·Science·Stephen M FlemingGeraint Rees
Apr 12, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Stephen M FlemingChristopher D Frith
Apr 12, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Stephen M Fleming, Raymond J Dolan
May 30, 2012·Brain : a Journal of Neurology·Mark J EdwardsKarl J Friston
Dec 1, 1998·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M R BrautigamJ Kleijnen
Feb 1, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Li Yan McCurdyHakwan Lau
Jul 5, 2013·Current Opinion in Neurology·Mark J EdwardsIsabel Pareés
Oct 18, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin BairdDaniel S Margulies
May 31, 2014·Science·Maël DonosoEtienne Koechlin
Aug 1, 2014·Frontiers in Human Neuroscience·Stephen M Fleming, Hakwan C Lau
Aug 15, 2015·Practical Neurology·Catherine PenningtonElizabeth Coulthard
Sep 25, 2015·Journal of Alzheimer's Disease : JAD·Catherine PenningtonElizabeth Coulthard
Sep 27, 2015·Psychological Science·Dobromir RahnevHakwan Lau
Oct 9, 2015·Journal of Alzheimer's Disease : JAD·Jon StoneAlan Carson
Apr 12, 2016·Journal of Alzheimer's Disease : JAD·Colette M SmartJodie R Gawryluk
Dec 19, 2016·Seizure : the Journal of the British Epilepsy Association·Markus Reuber, Richard J Brown
Mar 21, 2017·The International Journal of Neuroscience·Angela J Pereira-MoralesFrancisco Pereira-Manrique
Feb 10, 2018·International Journal of Geriatric Psychiatry·A J Larner
Nov 20, 2018·Neurodegenerative Disease Management·Viraj Bharambe, Andrew J Larner
Jan 1, 2019·Journal of Experimental Psychology. General·Jason CarpenterStephen M Fleming

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Citations

Jul 9, 2020·Cognitive Neuropsychiatry·Susannah PickLaura H Goldstein
Aug 14, 2020·Brain : a Journal of Neurology·Harriet A BallAlan J Carson
May 1, 2020·Neurodegenerative Disease Management·A J Larner
Oct 19, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Codruta BirleDafin F Muresanu
Apr 6, 2021·Parkinsonism & Related Disorders·Lucia RicciardiMark J Edwards
Jul 3, 2021·Brain Sciences·Harriet A BallCatherine M Pennington
Aug 3, 2021·Biological Psychiatry·Tricia X F SeowStephen M Fleming
Sep 18, 2021·CNS Spectrums·Laura McWhirterAlan Carson

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