Metal-free I2O5-mediated direct construction of sulfonamides from thiols and amines

Organic & Biomolecular Chemistry
Minghui ZhuHua Wang

Abstract

A simple and convenient method has been developed for the construction of sulfonamides via I2O5-mediated sulfonylation of amines with arylthiols. The present protocol provides an attractive approach to sulfonamides in moderate to good yields from readily accessible and easy to handle starting materials under mild and metal-free conditions.

References

Oct 3, 1999·Journal of Medicinal Chemistry·T OwaK Kitoh
May 11, 2000·Organic Letters·J Yin, S L Buchwald
Jan 11, 2002·Journal of Medicinal Chemistry·Bernard MasereelClaudiu T Supuran
May 23, 2002·Journal of the American Chemical Society·Jingjun Yin, Stephen L Buchwald
Jun 6, 2003·Medicinal Research Reviews·Claudiu T SupuranAndrea Scozzafava
Oct 11, 2003·The Journal of Organic Chemistry·Rina PandyaAnthony G M Barrett
Apr 16, 2004·Journal of Medicinal Chemistry·Dominique Guianvarc'hDaniel Dauzonne
Oct 19, 2006·Bioorganic & Medicinal Chemistry Letters·Nadeem SiddiquiMashooq A Bhat
Jan 16, 2007·The Journal of Organic Chemistry·Michael HarmataNathan L Calkins
Mar 17, 2007·European Journal of Medicinal Chemistry·Houxing FanRuyun Ji
Sep 20, 2008·Chemical Communications : Chem Comm·Biswajit KalitaKenneth M Nicholas
Feb 5, 2009·Journal of the American Chemical Society·Feng ShiMatthias Beller
Nov 19, 2009·The Journal of Organic Chemistry·Kiumars BahramiMehdi Soheilizad
Jan 6, 2010·European Journal of Medicinal Chemistry·Mahantesha BasanagoudaAshwini A Mohite
Mar 20, 2010·The Journal of Organic Chemistry·David A Powell, Hope Fan
Oct 30, 2010·Journal of the American Chemical Society·Bao NguyenMichael C Willis
Jan 12, 2011·Journal of the American Chemical Society·Bin XiaoLei Liu
Feb 24, 2011·The Journal of Organic Chemistry·Andrew J A WatsonJonathan M J Williams
Apr 23, 2011·The Journal of Organic Chemistry·Shashank ShekharSteven C Cullen
Sep 16, 2011·Journal of Medicinal Chemistry·Ashit K GangulyCorey Strickland
Jun 30, 2012·Chemical Communications : Chem Comm·Shengqing Ye, Jie Wu
Sep 5, 2012·Chemical Communications : Chem Comm·Shengqing Ye, Jie Wu
Jun 5, 2013·Chemical Communications : Chem Comm·Xiaodong TangHuanfeng Jiang
Mar 12, 2015·Bioorganic & Medicinal Chemistry·Mariusz MojzychPrzemysław Kalicki
Nov 5, 2015·Organic & Biomolecular Chemistry·Sirilata YotphanVichai Reutrakul
Jan 16, 2016·Organic Letters·Andy S TsaiVincent Mascitti
Jan 13, 2017·The Journal of Organic Chemistry·Pranab K Shyam, Hye-Young Jang

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Citations

May 29, 2018·Topics in Current Chemistry·Akram HosseinianEsmail Vessally
Apr 13, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Saiwen LiuJin Zhang
Mar 8, 2019·The Journal of Organic Chemistry·Xianzhu ZengJunfeng Zhao

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