Metal ion adducts in the structural analysis of ginsenosides by electrospray ionization with multi-stage mass spectrometry

Rapid Communications in Mass Spectrometry : RCM
Meng CuiS Liu

Abstract

The effect of metal (Li+, Na+, K+, Ag+) cationization on collision-induced dissociation of ginsenosides was investigated by electrospray ionization mass spectrometry combined with multi-stage mass spectrometry (ESI-MS(n)). The fragments of sodiated and lithiated molecules give valuable structural information regarding the nature of the aglycone and the sequence and linkage information of sugar moieties. However, the number and relative abundances of fragment ions from lithiated ginsenosides are significantly greater than for the sodiated species. The K+ adducts undergo glycosidic cleavages and very limited cross-ring reactions. The silver ion adducts fragment mainly through glycosidic cleavages.

References

Feb 1, 1995·Journal of Natural Products·R G Kerr, Z Chen
Feb 1, 1996·Journal of Mass Spectrometry : JMS·J WangR Guevremont
Mar 1, 1997·Biological & Pharmaceutical Bulletin·K MetoriS Takahashi
Jan 1, 1997·Rapid Communications in Mass Spectrometry : RCM·S NorthP Camilleri
Oct 31, 1998·Analytical Chemistry·D C van SettenG van de Werken
Dec 1, 1995·Journal of the American Society for Mass Spectrometry·X Li, E de Hoffmann
Mar 1, 1994·Journal of the American Society for Mass Spectrometry·P Hu, M L Gross

❮ Previous
Next ❯

Citations

Nov 16, 2001·Phytochemical Analysis : PCA
Apr 2, 2005·Analytical and Bioanalytical Chemistry·Robert Q ThompsonEdward White
Nov 24, 2004·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Nicola Fuzzati
Mar 5, 2013·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Guangyue HouShuying Liu
Jun 12, 2002·Journal of the American Society for Mass Spectrometry·Matthew C CrowePaul Hergenrother
Apr 11, 2003·Journal of the American Society for Mass Spectrometry·Rafał FrańskiOles P Szwajka
Jun 9, 2006·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Ji Hye GilJongki Hong
May 14, 2014·Marine Drugs·Yadollah BahramiChris Franco
May 29, 2007·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Liu YangXing Zeng
Mar 30, 2005·Rapid Communications in Mass Spectrometry : RCM·Fabrizio Dal PiazNunziatina De Tommasi
Sep 24, 2004·Rapid Communications in Mass Spectrometry : RCM·Fengrui SongShuying Liu
Nov 1, 2005·Rapid Communications in Mass Spectrometry : RCM·Noritaka HashiiToru Kawanishi
Jan 24, 2007·Rapid Communications in Mass Spectrometry : RCM·Eric C Y ChanHwee-Ling Koh
Jun 3, 2008·Rapid Communications in Mass Spectrometry : RCM·Felipe Augusto DörrErnani Pinto
Jan 3, 2013·Biomedical Chromatography : BMC·Andrey StavrianidiOleg Shpigun
Jan 25, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Tianxiu QianZhi-Hong Jiang
Jan 23, 2003·Rapid Communications in Mass Spectrometry : RCM·Geoffrey C KiteMonique S J Simmonds
Jun 14, 2008·Phytochemistry·Mo DanWei Jia
Jul 12, 2002·Journal of Mass Spectrometry : JMS·Xiu-Sheng MiaoRaymond E March
Aug 28, 2001·Journal of Mass Spectrometry : JMS
Oct 2, 2020·Rapid Communications in Mass Spectrometry : RCM·Yunpeng BaiChunbo Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.