PMID: 12752209May 20, 2003Paper

Metallic biomaterials TiN-coated: corrosion analysis and biocompatibility

Artificial Organs
André Luís PaschoalArtur de Jesus Motheo

Abstract

Corrosion processes due to contact with the physiological environment should be avoided or minimized in orthopedic implants. Four metallic substrates frequently used as biomaterials: pure Ti, Ti-6Al-4V alloy, ASTM F138 stainless steel, and Co-Cr-Mo alloy, were coated with TiN using the physical vapor deposition (PVD) technique. These coatings have been screened by polarization curves in physiological solutions. TiN prepared by PVD is efficient as coating for stainless steel. On titanium and alloy there are no benefits concerning the corrosion resistance compared to the bare Ti-materials. TiN coatings have been screened according to ISO 10993 standard tests for biocompatibility and exhibited no cytotoxicity, dermal irritation, or acute systemic toxicity response.

References

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Citations

Oct 18, 2011·Journal of Materials Science. Materials in Medicine·Claus MosekeAndrea Ewald
Apr 16, 2004·Artificial Organs·Paul S Malchesky
Jan 8, 2008·Dental Materials : Official Publication of the Academy of Dental Materials·Chia-Chi ChienKwok-Hung Chung
Dec 9, 2014·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Guy SovakAnna Weiss
Apr 10, 2009·The Journal of Chemical Physics·Janina ZimmermannLucio Colombi Ciacchi
Nov 8, 2017·Dental Materials Journal·Haruki SugisawaTeruko Takano-Yamamoto
Mar 6, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Leonardo C CampanelliArtur J Motheo
Dec 14, 2005·Journal of Biomedical Materials Research. Part a·Hung-I YehCheng-Ho Tsai
Dec 17, 2020·Frontiers in Bioengineering and Biotechnology·Wei-Hua WangWen-Yu Zhu
Jan 16, 2021·Acta Biomaterialia·Jose D AvilaAmit Bandyopadhyay
Jan 21, 2021·Journal of Materials Science. Materials in Medicine·Mustafa Şükrü KurtElif Arslan
May 29, 2018·Journal of the Mechanical Behavior of Biomedical Materials·Himanshu Sahasrabudhe, Amit Bandyopadhyay
Jun 18, 2019·ACS Applied Materials & Interfaces·Pascal M GschwendSotiris E Pratsinis
Aug 18, 2021·Stem Cell Reviews and Reports·Jitsuro TsukadaF Vogt

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