Metallic Transition Metal Dichalcogenide Nanosheets as an Effective and Biocompatible Transducer for Electrochemical Detection of Pesticide

Analytical Chemistry
Fengnian ZhaoJianfeng Ping

Abstract

Owing to their large specific surface, favorable electrical conductivity, and excellent electrocatalytic capabilities, two-dimensional transition metal dichalcogenides have received considerable attention in the field of biosensors. On the basis of these properties, we developed a portable and disposable enzyme-based biosensor for paraoxon detection using a metallic MoS2 nanosheets modified screen-printed electrode (SPE). The exfoliated ultrathin metallic MoS2 nanosheets can accelerate the electron transfer on electrode surface and contribute to the immobilization of acetylcholinesterase (AChE) via the cross-linking of glutaraldehyde. Electrodeposited gold nanoparticles (AuNPs) on SPE were used to immobilize MoS2 nanosheets through the interaction between Au atoms on AuNPs and S atoms on MoS2. Using acetylcholine as the substrate, AChE can catalyze the formation of electroactive thiocholine and further generate the redox current. In the presence of paraoxon, the activity of AChE can be inhibited, making the related electrochemical signals weaken. Under the optimized conditions, this electrochemical biosensor exhibited a favorable linear relationship with the concentration of paraoxon from 1.0 to 1000 μg L-1, with the detection ...Continue Reading

References

Jun 28, 2016·Analytical and Bioanalytical Chemistry·Qiqi ZhengYibin Ying
Oct 11, 2016·Archives of Toxicology·Sara Mostafalou, Mohammad Abdollahi
Feb 6, 2017·Analytical Biochemistry·Jyotsana MehtaAkash Deep

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Citations

May 22, 2020·Bulletin of Environmental Contamination and Toxicology·Qi YangYadong Yu
Jul 7, 2020·The Science of the Total Environment·Chao ZhangYibin Ying
Oct 6, 2020·Biosensors & Bioelectronics·Fengnian ZhaoJianfeng Ping
Nov 19, 2020·Chemical Society Reviews·Nasuha RohaizadMartin Pumera
Apr 4, 2021·International Journal of Molecular Sciences·Iruthayapandi Selestin RajaDong Wook Han
May 7, 2021·Analytical Methods : Advancing Methods and Applications·Tianlin Wang, Yaqing Liu
May 6, 2020·ACS Applied Materials & Interfaces·Fengnian ZhaoRaffaele Mezzenga
Sep 7, 2021·Analytical Methods : Advancing Methods and Applications·Monika BhattuDeepika Kathuria

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