Metastasis to sigmoid colon mucosa and submucosa from serous borderline ovarian tumor: response to hormone therapy

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
E-J LeeJ J Kavanagh

Abstract

Distant metastasis to sites other than lymph nodes of borderline ovarian tumor is rare. We describe a case metastasized to sigmoid colon mucosa and submucosa. The metastatic lesion was detected incidentally by screening colonoscopy 7 years after the patient was treated for the primary tumor. The metastatic lesion responded well to treatment with oral Arimidex 1 mg/day. A follow-up colonoscopy with biopsy and imaging studies after 3 months of treatment revealed no evidence of disease in the sigmoid colon. This case showed that the sigmoid colon mucosa and submucosa should be considered as one of distant metastatic sites of a serous borderline ovarian tumor and the favorable response to Arimidex provides support the use of hormone therapy in women with serous borderline ovarian tumor.

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Citations

Sep 27, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Y F LiJ J Kavanagh
Oct 2, 2012·The Oncologist·Daniela FischerovaDavid Cibula
Jun 14, 2014·BMJ Case Reports·Khashayar EsfahaniLawrence Panasci
Sep 4, 2007·Fertility and Sterility·Erica E MarshSerdar E Bulun
Jun 26, 2007·The Journal of Steroid Biochemistry and Molecular Biology·Serdar E BulunZhihong Lin
May 16, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher D SteevensSandeep Bahadur
Jan 24, 2014·Clinical Medicine Insights. Reproductive Health·Shakuntala Chhabra, Imran Kutchi

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