Metastatic adenocarcinoma in the cervical lymph nodes from an occult primary

Clinical Oncology : a Journal of the Royal College of Radiologists
R G Glynne-JonesR J Berry

Abstract

Cervical lymph node metastases as the only site of disease is a rare presentation of an adenocarcinoma of unknown primary origin. This retrospective analysis examines the records of ten consecutive patients at the Middlesex Hospital with this diagnosis between 1954 and 1986. The diagnostic protocol employed and the results of radical treatment are evaluated. Nine patients received radiation therapy with intent to cure, and one patient had a radical neck dissection. Overall actuarial survival for all patients (10) at 2 years was 23% and at 5 years 0%. Only two of the 10 patients subsequently revealed a primary tumour--both below the clavicles. Disease control above the clavicles was not achieved in a single patient despite radical treatment.

References

Jan 1, 1979·International Journal of Radiation Oncology, Biology, Physics·D G NordstromH B Latourette
Jan 1, 1979·Acta Radiologica: Oncology, Radiation, Physics, Biology·B JoseZ Frias
Oct 1, 1987·International Journal of Radiation Oncology, Biology, Physics·C S Hamilton, A O Langlands
Dec 1, 1986·International Journal of Radiation Oncology, Biology, Physics·L S CarlsonM J Oswald
Jan 1, 1981·Acta Radiologica. Oncology·P PaciniA Chiavacci
Oct 1, 1983·American Journal of Surgery·R H SpiroE W Strong
Jan 1, 1981·Archives of Otolaryngology·J TemplerW E Davis

❮ Previous
Next ❯

Citations

Jan 14, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·P Strojan, A Anicin
Feb 24, 2004·Acta Oto-laryngologica·Shun-Ichi Imamura, Haruko Suzuki
Jun 20, 2013·Ear, Nose, & Throat Journal·Hilmi Alper SenkalAhmet Bülent Sözeri
Mar 1, 1997·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·H J van der PlankenA B Karim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved