Metastatic behaviour of sinonasal adenocarcinomas of the intestinal type (ITAC)

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
K DonhuijsenH-G Schroeder

Abstract

The relative frequency of regional lymphogenic versus distant hematogenic metastases was evaluated in 369 patients with sinonasal adenocarcinoma of the intestinal type (ITAC). We assessed the results of neck dissections for a limited number of patients undergoing this surgical intervention. 117 ITAC patients were followed up for at least 5 years. Neck dissections were performed in 18 cases (15 primary and 3 secondary operations), 4 of which revealed carcinoma-positive lymph nodes. Metastases in lymph nodes were also diagnosed clinically in three other patients adding up to a total of seven individuals (6 % of 117) with lymphogenic metastases. In comparison, distant hematogenic metastases were identified in 15.4 % of these 117 patients. In the second group of 252 patients, the occurrence of distant hematogenic metastases and colorectal adenocarcinomas was registered but no formal follow-up procedure was applied. 50 neck dissections were performed in this group, 46 of which exhibited no histological evidence for metastases in lymph nodes, while in 1 case they were carcinoma-positive. Three additional cases showed clinical signs of metastases in regional lymph nodes. Taken together, our observations indicate that regional lymphoge...Continue Reading

References

Mar 1, 1986·The American Journal of Surgical Pathology·L Barnes
Feb 23, 1999·International Journal of Occupational and Environmental Health·C L SimpsonR K Peters
Mar 21, 2000·American Journal of Industrial Medicine·K InnosD A Leon
Oct 20, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Sue S YomAdel K El-Naggar
Feb 10, 2006·The Annals of Otology, Rhinology, and Laryngology·Vicente A RestoDerrick T Lin
Feb 22, 2008·BMC Cancer·Jette BornholdtHåkan Wallin
May 27, 2008·Acta otorrinolaringológica española·José Luis LlorenteCarlos Suárez
Nov 30, 2011·Rhinology·Juan Pablo Díaz-MolinaMario A Hermsen
Oct 12, 2012·Cellular Oncology (Dordrecht)·Cristina García-InclánMario A Hermsen
Mar 6, 2013·International Journal of Molecular Sciences·Vanessa SzablewskiValérie Costes
Apr 18, 2013·Journal of Surgical Oncology·Adedayo A OnitiloSuhail A R Doi
Jun 13, 2014·International Journal of Cancer. Journal International Du Cancer·Colleen WebberPatti A Groome

❮ Previous
Next ❯

Citations

Apr 5, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·K DonhuijsenH-G Schroeder
Jul 1, 2016·Head and Neck Pathology·Stephen M SmithO Hans Iwenofu
Feb 6, 2017·Surgical Pathology Clinics·Edward B Stelow
Sep 6, 2017·Advances in Therapy·Fernando LópezAlfio Ferlito
Feb 2, 2018·Current Opinion in Otolaryngology & Head and Neck Surgery·Vittorio RampinelliPiero Nicolai
Jan 4, 2020·Journal of Neuro-oncology·Marco FerrariPiero Nicolai
Oct 15, 2020·Journal of Cancer Research and Clinical Oncology·Sannia SjöstedtChristian von Buchwald
Sep 28, 2021·ANZ Journal of Surgery·Jamie MillerJorn Van Der Veken

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Christopher-Philipp NobisMarco R Kesting
Annals of Coloproctology
Kyung Ha LeeJi Yeon Kim
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Yusuf VayisogluKoray Ocal
© 2022 Meta ULC. All rights reserved