Metastatic breast cancer masquerading as gastrointestinal primary

The American Journal of Gastroenterology
R E SchwarzA D Turnbull

Abstract

Seven patients with metastatic breast cancer presenting as gastrointestinal primary are described. These included six gastric and one colonic lesions. None of the patients had known systemic metastases at the time of diagnosis. The mean age at presentation was 66.7 yr (range 55-78). Median interval between breast cancer and gastrointestinal metastasis diagnosis was 6 yr (range 0.25-12.5). Original breast cancer histology included infiltrating lobular cancer (n = 4), infiltrating ductal cancer (n = 1), and a mixed type (n = 2). All patients with gastric involvement presented with epigastric pain and early satiety; the patient with colonic involvement had heme-positive stool. In three cases of gastric tumor and the one case of colonic tumor presentation, a definitive diagnosis of metastatic breast cancer was only confirmed after surgical resection of a presumed primary gastric or colonic malignancy. In the other three cases, pathological diagnostic confirmation was obtained through endoscopic biopsies and comparison to breast biopsy material, and operative treatment was avoided in favor of systemic cytotoxic therapy. The diagnosis was confirmed through similarities between mammary and gastric histopathology with regard to growth ...Continue Reading

References

Oct 1, 1975·The American Journal of Digestive Diseases·L S Menuck, J R Amberg
Nov 1, 1992·Journal of Surgical Oncology·A S GifaldiG R Wolfe
Mar 1, 1992·Gastrointestinal Endoscopy·B G TaalH Peterse
May 1, 1991·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A R Kagan, R J Steckel
Apr 1, 1988·Journal of Clinical Gastroenterology·R M HansenR A Komorowski
May 1, 1988·Diseases of the Colon and Rectum·M Y RabauY Yossipov
Apr 1, 1986·Cancer·A TokunagaK Hayashi
Jun 1, 1973·The Japanese Journal of Surgery·T HattoriN Kaibara
Oct 1, 1972·The American Journal of Digestive Diseases·M S Klein, P Sherlock
Oct 1, 1968·The American Journal of Digestive Diseases·H L DavisB C Korbitz
Feb 1, 1984·The American Journal of Surgical Pathology·A K LeeH J Wolfe
Dec 1, 1993·Archives of Surgery·H L BumpersE D Holyoke
Jan 1, 1996·CA: a Cancer Journal for Clinicians·S L ParkerP A Wingo

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Citations

Jan 1, 2012·Journal of Surgical Case Reports·Ss RajanM Mestrah
Oct 24, 2012·International Journal of Breast Cancer·Massimo AmbroggiLuigi Cavanna
Nov 2, 2012·World Journal of Surgical Oncology·Ikuo MatsudaSeiichi Hirota
Jul 11, 2007·World Journal of Surgical Oncology·Gregory E JonesRobert C Mason
Jul 26, 2008·World Journal of Surgical Oncology·Antonio CiullaGaspare Genova
Mar 19, 2009·World Journal of Gastroenterology : WJG·Maria PuglisiGiacomo Borgonovo
Jan 22, 2014·International Surgery·Vilvapathy Senguttuvan KarthikeyanNagarajan Rajkumar
Jan 7, 2014·World Journal of Surgical Oncology·Carlo MolinoUNKNOWN Breast Unit Cardarelli Hospital, Naples, Italy
Feb 2, 2012·International Journal of Breast Cancer·W EljabuN Vaingankar
Jan 14, 2010·Case Reports in Medicine·Lonzetta NealCarol Reynolds
Nov 28, 2012·World Journal of Surgical Oncology·Xiao-cong ZhouYi Jiang
Jul 2, 2010·Case Reports in Medicine·M A TitiA D Newland
Mar 25, 2015·Journal of Surgical Case Reports·Sala AbdallaCynthia-Michelle Borg
Jan 16, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Arifa AbidDulabh K Monga
Nov 10, 2011·São Paulo Medical Journal = Revista Paulista De Medicina·Charlene TroianiGisele Alborghetti Nai
Sep 17, 2008·International Journal of Surgical Pathology·Lorenzo DanieleSofia Asioli
May 7, 2002·The Journal of the Royal Society for the Promotion of Health·I R DanielsE M Chisholm
Apr 19, 2016·Journal of Investigative Medicine High Impact Case Reports·Bathmapriya BalakrishnanIrina Burman-Solovyeva
Aug 27, 2003·Southern Medical Journal·Moustapha TohfeMichel Saade
Apr 30, 2013·Case Reports in Gastroenterology·A Nikkar-EsfahaniRobert G Wilson
Aug 19, 2011·Journal of breast cancer·Jung Eun ChoiMin Kyoung Kim
Jun 21, 2007·World Journal of Surgery·A A AyantundeN T Welch
Aug 11, 2007·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Tetsuro KobayashiSyusei Tominaga
Oct 9, 2007·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·J M BalibreaJ L Balibrea
Nov 20, 2004·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Tetsuro KobayashiShiro Adachi
Feb 17, 2010·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Maite López DeograciasFrancisco Martínez García
Sep 24, 2005·Annals of Surgical Oncology·Elisabeth C McLemoreJohn H Donohue
Apr 6, 2001·Diseases of the Colon and Rectum·G CerviS M Giulini
Mar 25, 2006·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Paulo Moacir de Oliveira CampoliOrlando Milhomem da Mota
Jul 31, 2013·Surgery Today·Tsutomu Namikawa, Kazuhiro Hanazaki
Jun 4, 2011·International Journal of Clinical Oncology·Ruping ZhaoXiaomao Guo
Mar 25, 2011·Surgery Today·Masayuki OkidoHitoshi Ichimiya
Oct 22, 2016·Journal of Surgical Oncology·Ali El-HageÉric Poirier
Oct 19, 2013·Experimental and Therapeutic Medicine·Liqiong LvZhongyi Peng
Apr 22, 2014·Digestive Diseases and Sciences·Bing ZhangBrigid S Boland
Dec 14, 2016·Case Reports in Gastrointestinal Medicine·Masahide KitaHiroyuki Okada
Aug 1, 2013·Clinical Journal of Gastroenterology·Tsutomu TakedaNaomi Uemura
Apr 29, 2016·Molecular and Clinical Oncology·Jun NakamuraHirokazu Noshiro
Jan 25, 2019·Oncology Letters·Joohyun HongYeon Hee Park

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