Abstract
From 1974 to 1984, 31 patients with metastatic carcinoma to the neck from an unknown primary were treated with radiation therapy. On review, three groups were identified based on presentation and treatment. Group I consists of 19 patients treated with curative intent. They all presented with cervical adenopathy, 11 patients with N1 disease, 2 with Stage N2A disease, 1 with Stage N2B disease, 4 with N3A disease, and 1 with unknown stage. The majority of patients were treated with portals encompassing the nasopharynx, oropharynx, hypopharynx, and neck to a dose of 5000 rad followed by boosts of 1000-1500 rad. The overall 2-year NED survival in this group was 63% (12/19). The most significant prognostic factor was the stage of the metastatic nodes. The NED survival rate for the 14 patients with Stage N1 and N2 was 86% (12/14). Histology of the lesions was not an important factor in the outcome. In Group II there are six patients who received palliative treatment because of large, fixed, cervical nodes. Three of these patients (50%) died within 2 months of completion of treatment. Group III consists of six patients who presented with supraclavicular adenopathy. All had persistent or recurrent disease within 19 months. We have concl...Continue Reading
References
Mar 11, 1975·The Annals of Otology, Rhinology, and Laryngology·M P FriedJ H Ogura
Mar 1, 1974·Radiology·P J Fitzpatrick, J F Kotalik
Apr 1, 1973·Cancer·R H JesseG H Fletcher
Oct 1, 1970·American Journal of Surgery·J R BarrieE W Strong
Jan 1, 1981·Acta Radiologica. Oncology·P PaciniA Chiavacci
Citations
Mar 14, 2002·Head & Neck·Shahrokh IganejThomas Morgan
Apr 5, 2002·Head & Neck·Chi-Chung TongWai-Hon Lau
Jan 1, 1994·Head & Neck·C NguyenM Yassa
Jan 1, 1991·Journal of Cancer Research and Clinical Oncology·J E Ultmann
Jun 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·L WeirP Warde
Mar 1, 1997·International Journal of Radiation Oncology, Biology, Physics·S P Reddy, J E Marks
Oct 6, 1997·International Journal of Radiation Oncology, Biology, Physics·M LapeyreP Bey
Jan 25, 2000·Oral Oncology·M P StokkelP P van Rijk
Jul 22, 1993·The New England Journal of Medicine·J D Hainsworth, F A Greco
Feb 6, 2010·Japanese Journal of Clinical Oncology·Tomomasa HayashiSatoshi Ebihara
Sep 15, 2010·Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology·Pragya ShuklaMahendra Pal Singh Negi
Mar 1, 1997·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·H J van der PlankenA B Karim
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·J R CosterL W DeSanto
Oct 1, 1990·International Journal of Radiation Oncology, Biology, Physics·V A Marcial-VegaS E Thawley
Jan 1, 1990·Current Problems in Cancer·C D JacobsW E Fee
Feb 16, 2006·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Paolo Boscolo-RizzoCarlo Marchiori
Feb 11, 2000·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·M AmichettiR Valdagni
Jul 15, 1989·Cancer·F de BraudM al-Sarraf
Feb 3, 2007·Head & Neck·Maryam AslaniGeorge Shenouda
Aug 1, 1993·Journal of Chemotherapy·B JeremicJ Marinkovic
Apr 26, 2001·Acta Oncologica·S FrieslandJ O Fernberg
Feb 1, 1992·Journal of Chemotherapy·B JeremicL J Mijatovic
Jul 1, 1997·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·M J KirschnerR Sauer
Jan 1, 1992·Acta Oncologica·J JakobsenK Jørgensen
Dec 1, 1992·Journal of Chemotherapy·B JeremicS Jevremovic
Jan 12, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D A RandallP J Martin
Apr 1, 1994·Cancer Treatment Reviews·G Daugaard