Metastatic clear cell renal cell carcinoma in isolated retroperitoneal lymph node without evidence of primary tumor in kidneys: A case report

World Journal of Clinical Oncology
Lisa Be Shields, Arash Rezazadeh Kalebasty

Abstract

Retroperitoneal lymph node dissection (RPLND) plays a diagnostic, therapeutic, and prognostic role in myriad urologic malignancies, including testicular carcinoma, renal cell carcinoma (RCC), and upper urinary tract urothelial carcinoma. RCC represents 2% of all cancers with approximately 25% of patients presenting with advanced disease. Clear cell RCC (CCRCC) is the most common RCC, accounting for 75%-80% of all RCC. A 71-year-old man presented with a history of benign prostatic hypertrophy. He was asymptomatic without any hematuria, pain, or other urinary symptoms. A computed tomography (CT) scan of the abdomen and pelvis showed a 1.8 cm left retroperitoneal lymph node. There was no evidence of renal pathology. A core biopsy was performed of the left para-aortic lymph node. Although the primary tumor site was unknown, the morphological and immunohistochemical features were most consistent with CCRCC. A RPLND was performed which revealed a single mass 5.5 cm in greatest dimension with extensive necrosis. The retroperitoneal lymph node was most compatible with CCRCC. A nephrectomy was not conducted as a renal mass had not been detected on any prior imaging studies. The patient did not receive any type of adjuvant therapy. The p...Continue Reading

References

Aug 10, 2006·Abdominal Imaging·D M KohJ E Husband
Mar 6, 2007·Surgical Oncology Clinics of North America·Niels-Erik B JacobsenJohn P Donohue
Jan 25, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Rodney H Reznek
Sep 6, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M BianchiP I Karakiewicz
Apr 16, 2013·Journal of the Egyptian National Cancer Institute·Ashraf Hamid Ibrahim, Abd Elhamid H Ezzat
Jun 22, 2013·Contemporary Oncology Współczesna Onkologia·Anna Daria JaniszewskaAleksander Wasiutyński
Jul 31, 2013·Cancer Causes & Control : CCC·Michael R AbernThomas J Polascik
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Blanca Paño BrufauCarlos Nicolau Molina
May 21, 2014·BJU International·Riaz J KarmaliJose A Karam
Jan 27, 2015·European Urology·Borje LjungbergAxel Bex
Feb 4, 2016·Respirology Case Reports·Sook Fen OngRichard Wai Wing Lee
Dec 17, 2016·JAAD Case Reports·Hasan KhosraviGenevieve M Boland
Jan 9, 2019·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
biopsy

Related Concepts

Related Feeds

Adenocarcinoma, Clear Cell

Clear Cell Adenocarcinoma is a tumor that arises in the female genital tract and is characterized by cells that appear clear under the microscope. Discover the latest research here.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
B FallB-A Diagne
The Canadian Journal of Urology
Sapan N AmbaniRonald L Hrebinko
Journal of the American Society of Nephrology : JASN
Susie L HuAmerican Society of Nephrology Onco-Nephrology Forum
© 2021 Meta ULC. All rights reserved