Metastatic colorectal cancer to the small bowel-an uncommon cause of obscure GI bleeding: a three-case experience with review of the literature.

Journal of Gastrointestinal Cancer
Matthew N ThomaRoger J Charles

Abstract

Metastatic colorectal cancer to the small intestine is a rare condition presenting with nonspecific symptoms such as obscure gastrointestinal bleeding (OGIB). We report our experience with the use of capsule endoscopy (CE) and double-balloon enteroscopy (DBE) to identify and diagnose the metastatic colorectal cancer to the small bowel. The aim was to demonstrate the approach to the diagnosis of metastatic colorectal cancer to the small bowel including literature review. This is a retrospective case series from an academic tertiary referral center. Three patients with a history of colorectal cancer referred for OGIB underwent CE and subsequent DBE. All patients underwent evaluation including esophagogastroduodenoscopy and colonoscopy prior to referral. In each case, CE was performed revealing the source of bleeding which was confirmed as metastatic colorectal cancer to the small bowel by DBE. Significant lag time was noted from the initial diagnosis of colorectal cancer to the onset of symptomatic small bowel metastasis in this series (1.3-7 years). We found the incidence of metastatic colorectal cancer to the small intestine of those with small intestine tumors to be 6%. Clinicians should be suspicious of this condition in any ...Continue Reading

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Citations

Jul 18, 2015·Clinical Journal of Gastroenterology·Akihiro ArakiMamoru Watanabe
Jul 7, 2011·World Journal of Gastrointestinal Oncology·Sujith V CherianStephen K Landas
Feb 20, 2016·Annals of the Royal College of Surgeons of England·A-W N Meshikhes, A A Joudeh
May 6, 2016·Frontiers in Human Neuroscience·Renate M van de VenBen A Schmand
Jun 21, 2019·International Cancer Conference Journal·Harunobu SatoIchiro Uyama
Oct 20, 2017·Molecular and Clinical Oncology·Paraskevas StamopoulosGeorgios C Sotiropoulos
Feb 28, 2017·Intestinal research·Jen-Wei Chou, Ken-Sheng Cheng

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