Metastatic Disease in the Stomach

Gastrointestinal Tumors
Joche Weigt, Pete Malfertheiner

Abstract

Gastric metastases are rare and represent a late and progressed stage of malignant disease. This review highlights epidemiological, clinical and endoscopic findings as well as therapeutic strategies for metastatic disease of the stomach. The clinical presentation of gastric metastases is highly unspecific. The endoscopic appearance of gastric metastases is heterogeneous, but the most prevalent findings are solitary and submucosal lesions in the gastric wall. The most prevalent primary tumor spreading to the stomach is breast cancer, followed by renal cell cancer and many others. In general, gastric metastases occur in a late stage of malignant disease and frequently indicate short survival. Specific therapy for gastric metastases does not exist and is mainly performed with chemotherapy according to the primary tumor. Compared with other metastatic diseases, gastric metastases of renal cell cancer and breast cancer need distinct consideration. Gastric metastasis of these cancers presents with a better prognosis, as patients with these conditions can be offered effective chemotherapeutic treatment. Gastric metastatic disease is a rare clinical presentation. The pathophysiology of gastric metastatic seeding is not well understood....Continue Reading

Citations

Jul 28, 2016·Journal of Medical Case Reports·T KarraschS Gattenlöhner
Jan 10, 2017·Journal of Gastrointestinal Cancer·Mohamed Seenikatty Abdul HakimSanjiv Mahadeva
Feb 28, 2018·Clinical Nuclear Medicine·Hugo Enrique Solis LaraRocío Del Carmen Argueta Ruiz
Feb 13, 2018·Molecular and Clinical Oncology·Francesca SarocchiCord Langner
Jun 27, 2019·Scottish Medical Journal·A McLarenJ White
Jan 7, 2017·World Journal of Gastroenterology : WJG·Wei-Zhong ShengWei-Dong Gao
May 20, 2020·Journal of Gastrointestinal Cancer·Eric Omar ThenVinaya Gaduputi
Apr 4, 2017·International Cancer Conference Journal·Sho UeharaJunji Yonese
Jan 9, 2021·Curēus·Kevin GroudanKirti Joshi
Nov 17, 2020·World Journal of Gastrointestinal Surgery·Claudio IsopiGiorgio Ercolani

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