Abstract
Metastases to the gastrointestinal tract rarely occur in breast cancer except in invasive lobular carcinoma. The present study reports a rare case of metastatic gastric cancer from invasive ductal carcinoma (IDC) of the breast mimicking primary gastric linitis plastica. A 51-year-old premenopausal female, who had a history of partial mastectomy for right breast cancer at the age of 40, was referred to Toyama City Hospital (Toyoma, Japan) for an endoscopic diagnosis of gastric linitis plastica. Abdominal computed tomography (CT) revealed left hydronephrosis, while peritoneal metastasis and malignant ascites were not detected. Chest CT detected a left lung tumor, which had invaded the left upper bronchus. Biopsy specimens were obtained and the histopathological findings on both the gastric tumor and lung tumor demonstrated poorly differentiated adenocarcinoma, whereas the histology of the original breast cancer was IDC with a solid-tubular type. Immunohistochemistry revealed that the biopsied specimens of the gastric and lung tumors were positive for estrogen receptor (ER), progesterone receptor (PgR) and negative for human epithelial growth factor receptor-2 (HER2). These molecular characteristics indicated the case was metastat...Continue Reading
References
Oct 1, 1975·The American Journal of Digestive Diseases·L S Menuck, J R Amberg
Jan 1, 1992·Surgery Today·M MatsuiT Takahashi
Apr 1, 1990·Radiology·M S LevineH Herlinger
Apr 1, 1986·Cancer·A TokunagaK Hayashi
Feb 1, 1995·Journal of Surgical Oncology·K KitamuraM Saku
Jan 1, 1993·Gastrointestinal Endoscopy·S Madeya, G Börsch
Jul 5, 2001·Endoscopy· OdaT Shimoda
Apr 9, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·T Tot
Mar 25, 2006·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Paulo Moacir de Oliveira CampoliOrlando Milhomem da Mota
Dec 5, 2006·World Journal of Gastroenterology : WJG·Giovanni D De PalmaGiovanni Persico
Jul 11, 2007·World Journal of Surgical Oncology·Gregory E JonesRobert C Mason
Mar 21, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C SimmonsM J Clemons
Mar 30, 2010·The Breast : Official Journal of the European Society of Mastology·Shi Yun ChiaPuay Hoon Tan
May 28, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Maher M AlmubarakPascale Mariani
Nov 30, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Eitan AmirMark Clemons
Dec 20, 2011·Cancer Treatment Reviews·Eitan AmirAlastair M Thompson
Jan 22, 2013·Human Pathology·Ming-Hua LuoGary M Tse
Jan 30, 2013·Cancer Biology & Therapy·Julie M Galvis-JiménezSandra R Ramírez-Clavijo
Oct 15, 2013·The Journal of Pathology·Margaret C CummingsSunil R Lakhani
May 23, 2014·PloS One·Laure de DeckerOlivier Beauchet
Aug 15, 2014·Oncology Letters·Linshen TanXiaodong Xie
Citations
Feb 9, 2020·Journal of Gastrointestinal Cancer·Abigail GoSofia Ghani
Oct 11, 2016·Journal of breast cancer·Biagio RicciutiGiulio Metro
Jan 22, 2017·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Masayuki InoueToshio Oyama
Jan 12, 2021·Curēus·Luis GeadaLuis S Nasiff