Metastatic primary angiosarcoma of the breast in a pediatric patient with a complete response to systemic chemotherapy and definitive radiation therapy: case report and review of the literature

Journal of Pediatric Hematology/oncology
Heather G GatcombeNatia Esiashvili


We present a case of a rare malignancy, primary breast angiosarcoma, in a 15-year-old girl. She presented with a locally advanced tumor and suspected metastatic disease to the mediastinum and bones on PET imaging. The patient was treated with systemic chemotherapy and definitive radiation therapy to her left breast and achieved a complete response. She has no evidence of disease recurrence 44 months from her initial diagnosis.


Jul 15, 1980·Cancer·K T ChenJ J Bocian
Oct 20, 1993·International Journal of Radiation Oncology, Biology, Physics·P A JohnstoneT F DeLaney
Apr 6, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G LamblinJ Y Bobin
Feb 12, 2002·Clinical Nephrology·N MatsuzawaY Nakamoto
Jul 9, 2002·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E de BreeE J Th Rutgers
Aug 31, 2004·Journal of Surgical Oncology·Manoj PandeyBalakrishnan Rajan
Nov 17, 2005·Cancer·Stephan A VorburgerJanice N Cormier
Jun 2, 2007·Cancer·Taimur SherAna M Gonzalez-Angulo
Jan 24, 2008·AJR. American Journal of Roentgenology·Katrina N GlazebrookCarol Reynolds


Jun 28, 2011·Journal of Laboratory Physicians·B N Gayathri, Kadam Satyanarayan Rao
Jul 19, 2012·Journal of breast cancer·Eleonora CucciGiuseppina Sallustio
Oct 30, 2018·Clinical Nuclear Medicine·Thibaut Cassou-MounatNina Jehanno

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