Abstract
We reviewed 32 cases where a forensic autopsy detected methamphetamine in the blood, and all of these autopsies were performed at two institutes between 1991 and 2003. In accordance with several criteria, the blood concentration in 11 cases was classified as above the toxic level, and 10 of these cases were diagnosed as methamphetamine poisoning. In 20 cases (62.5% of total cases), the blood concentration was of a 'toxic level', and 10, 2 and 1 of these cases were diagnosed as methamphetamine poisoning, cardiomyopathy and intracerebral hemorrhage, respectively. Since it is unclear how the effects of methamphetamine may contribute to the death of an individual, a diagnosis of the exact cause of death is often difficult to make in cases where the blood concentration of methamphetamine was of a 'toxic level'. Therefore, a diagnosis has to be carefully made in consideration of the pathological findings, the pharmacological effects of methamphetamine and the process until death in such cases. Additionally, the mechanism of methamphetamine-related death needs to be more fully studied to enable an appropriate diagnosis to be made easily.
References
Dec 1, 1989·Clinical Cardiology·L J Jacobs
Jan 18, 1985·Journal of Chromatography·M Terada
Nov 5, 1970·The New England Journal of Medicine·B P CitronB J Haverback
Jan 1, 1993·Annual Review of Pharmacology and Toxicology·L S SeidenG A Ricaurte
Jan 1, 1997·Journal of Analytical Toxicology·K HaraM Kageura
Mar 25, 2000·Journal of Analytical Toxicology·F Moriya, Y Hashimoto
Aug 10, 2000·International Journal of Legal Medicine·Y MaenoR Matoba
Jul 10, 2001·Psychopharmacology·S D ComerM W Fischman
Oct 24, 2001·Forensic Science International : Synergy·C L WinekT W Balzer
Jan 10, 2002·The American Journal of Emergency Medicine·Emmanuel Atta AgabaTim Jackson
Sep 24, 2002·Forensic Science International : Synergy·Fumio Moriya, Yoshiaki Hashimoto
Aug 6, 2003·Medicine, Science, and the Law·Naoki NishidaRie Esaki
Nov 16, 2004·Annals of the New York Academy of Sciences·J Yamamoto
Dec 4, 2004·The American Journal of Forensic Medicine and Pathology·Shawn M McGeeMichael B McGee
Jan 12, 2005·Journal of Toxicology. Clinical Toxicology·John Kashani, Anne-Michelle Ruha
Feb 15, 2005·The Journal of Emergency Medicine·Keiko OhtaShuji Kishida
Jan 1, 1995·British Journal of Neurosurgery·F Selmi K G Davies R R Sharma J W Neal
Citations
Sep 26, 2013·Naunyn-Schmiedeberg's Archives of Pharmacology·Vida MashayekhiMir-Jamal Hosseini
Feb 9, 2012·Journal of Biomedical Science·Faith C H LiAlice Y W Chang
Jan 26, 2012·PloS One·Faith C H LiAlice Y W Chang
Sep 21, 2010·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Leo J SchepD Michael G Beasley
Jan 19, 2012·Disease-a-month : DM·David VearrierDavid A Haggerty
Feb 1, 2012·Neurotoxicology and Teratology·Mark S LeviJohn F Bowyer
Feb 11, 2010·Legal Medicine·Kotaro ShinoneMasayuki Nata
Oct 27, 2007·European Journal of Pharmacology·Ivan T LeeJohn A Schetz
May 12, 2009·Addiction·Christopher C Cruickshank, Kyle R Dyer
Jan 30, 2009·Journal of Forensic Sciences·Jennifer L PilgrimMarc Bollmann
Feb 10, 2012·Orvosi hetilap·Katalin KovácsEva Margit Kereszty
Dec 10, 2013·Forensic Science International : Synergy·J PietschU Schmidt
Feb 3, 2009·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Shao-hua YiQian Liu
Sep 7, 2013·Pharmacology·Tao LvJie Bai
Nov 14, 2006·Congenital Anomalies·Chun CuiYoshihiro Fukui
Dec 11, 2019·Journal of Medical Entomology·Shiwen WangYadong Guo
Apr 9, 2013·Molecular Medicine Reports·Masafumi TomitaTakaki Ishikawa
Nov 18, 2016·Frontiers in Neuroscience·Shkelzen ShabaniTamara J Phillips
Jun 2, 2018·Scientific Reports·Sayaka NagasawaHirotaro Iwase
Jul 9, 2010·Toxicology Mechanisms and Methods·Ruobing LiangBo Zhu