Methamphetamine suppression and route of administration: precursor regulation impacts on snorting, smoking, swallowing and injecting

Addiction
James K CunninghamMyra Muramoto

Abstract

The route of drug administration affects risk for dependence and medical harm. This study examines whether routes used by methamphetamine treatment participants were impacted by a major drug suppression policy-federal regulation of the methamphetamine precursor chemicals ephedrine and pseudoephedrine. Autoregressive-integrated moving average (ARIMA) intervention time-series analysis. California (1992-2004). Ephedrine single-ingredient products regulation, implemented August 1995; ephedrine with other active medicinal ingredients regulation, implemented October 1996; pseudoephedrine products regulation, implemented October 1997. Monthly counts of non-coerced methamphetamine treatment admissions reporting snorting, smoking, swallowing or injecting. Findings After rising sharply, snorting, smoking, swallowing and injecting admissions dropped 50%, 43%, 26% and 26%, respectively, when the 1995 regulation was implemented. Snorting also dropped 38% at the time of the 1997 regulation. Snorting, swallowing and injecting remained at lower levels to the end of the study period. Smoking resurged (40%) at the time of the 1996 regulation and continued rising. Precursor regulation was associated with changes in the administration of methamphe...Continue Reading

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Citations

Jun 13, 2009·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Melanie L RuschStefanie A Strathdee
Mar 16, 2012·Journal of Analytical Toxicology·Eunyoung HanJoon Myong Song
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Feb 25, 2018·Drug and Alcohol Dependence·Ricky N BluthenthalAlex H Kral

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