Methanol extracts from the resurrection plant Haberlea rhodopensis ameliorate cellular vitality in chronologically ageing Saccharomyces cerevisiae cells

Biogerontology
Milena GeorgievaGeorge Miloshev

Abstract

Bioactive substances that are found in many natural plant extracts are very important for the cosmetics, pharmaceutical industry and biotechnology. Especially interesting for these industries are the substances that possess cell revitalizing and anti-ageing properties. The endemic plant Haberlea rhodopensis is known for its ability to withstand drought and to revitalize when returned to optimal conditions after a long time in desiccation. It is a mere fact that this plant not only can completely resurrect from a dried state but is also able to bring back the natural biochemical compositions of its cells. As a result H. rhodopensis offers a wide field for investigation of the exact mechanisms of the revitalization process as well as broadens the search for unique bioactive chemical substances in its cells. Here, by using the yeast Saccharomyces cerevisiae as a model we have demonstrated that methanol extracts from the plant H. rhodopensis hold specific properties to revitalize and ameliorate cellular growth as well as to balance intracellular metabolic states. Our results add valuable knowledge on the effects of natural compounds on ageing and reinforce the idea of using yeast as a model organism in the development of rapid test...Continue Reading

References

Nov 23, 2000·Mechanisms of Ageing and Development·H Gershon, D Gershon
May 23, 2008·International Journal of Cosmetic Science·A D Russell
Sep 13, 2008·Biochimica Et Biophysica Acta·Sheena Claire Li, Patricia M Kane
Aug 6, 2010·Trends in Cell Biology·John Armstrong
Oct 26, 2011·International Journal of Cosmetic Science·G Dell'Acqua, K Schweikert
Nov 19, 2011·Sub-cellular Biochemistry·Valter D Longo, Paola Fabrizio
Dec 28, 2011·Biochimica Et Biophysica Acta·Milena GeorgievaGeorge Miloshev
Mar 7, 2012·FEMS Yeast Research·Austen R D GanleyTakehiko Kobayashi
Jun 30, 2012·FEMS Yeast Research·Clara PereiraLucília Saraiva
Sep 13, 2012·Oxidative Medicine and Cellular Longevity·Vanessa PalermoCristina Mazzoni
Sep 22, 2012·Cellular and Molecular Life Sciences : CMLS·Tsanko S GechevValentina Toneva
Jan 8, 2013·Frontiers in Oncology·Cristina MazzoniClaudio Falcone
Jul 3, 2013·IUBMB Life·Anna Leonov, Vladimir I Titorenko
Sep 12, 2013·Oxidative Medicine and Cellular Longevity·Katya UzunovaGeorge Miloshev
Oct 2, 2013·Current Pharmaceutical Design·Gabriella TestaElena Chiarpotto
Oct 15, 2013·Pharmacognosy Magazine·Magdalena Kondeva-BurdinaMitka Mitcheva
Dec 5, 2013·Frontiers in Oncology·Manuela Côrte-Real, Frank Madeo
Dec 24, 2013·Oxidative Medicine and Cellular Longevity·Cristina MazzoniPaula Ludovico
Apr 17, 2014·Physiologia Plantarum·Daniela MoyankovaDimitar Djilianov
Sep 6, 2014·ELife·Kiersten A HendersonDaniel E Gottschling
May 29, 2015·Biotechnology, Biotechnological Equipment·Ralitsa VelevaTanya Topouzova-Hristova

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