PMID: 45683Nov 1, 1978

Methemoglobinemia: nitrobenzene ingestion

JACEP
M A SchimelmanH A Muller

Abstract

In an unusually severe case of multiple toxin ingestion, a 48-year-old man ingested approximately 300 cc of Hoppe's Gunpower Solvent #9, which contains kerosene, denatured ethyl alcohol, oil and nitrobenzene. The major manifestation was nitrobenzene-induced methemoglobinemia of rapid onset. Treatment involves the judicious use of 1% methylene blue plus, in severe cases, hemodynamic and ventilatory support. The patient recovered after 48 hours and was transferred to the psychiatric service with continued follow-up for a mild poison-induced hemolytic anemia.

References

Jan 1, 2009·BMJ Case Reports·Mark PereraAndrew Dawson
Jun 1, 1995·Journal of Accident & Emergency Medicine·R J Edwards, J Ujma
Jan 1, 1992·Journal of Toxicology. Clinical Toxicology·B S DeanE P Krenzelok
Jun 22, 2010·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Shingo ArakawaWataru Takasaki

Citations

Sep 23, 1948·The New England Journal of Medicine·C A FINCH

Related Concepts

Nitrobenzenes
Toxin
Poisoning
Nitrobenzene
Kerosolenum, kerosene, Homeopathic preparation
Combined Modality Therapy
Psychiatry Specialty
Ingestion
Solvents
Denatured ethanol

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