Methicillin-resistant staphylococci and ofloxacin-resistant bacteria from clinically healthy conjunctivas

Ophthalmic Research
K WatanabeS Hayasaka

Abstract

We evaluated the existence of methicillin (DMPPC)-resistant staphylococci and ofloxacin (OFLX)-resistant bacteria among preoperative patients at an eye clinic. Bacterial growth was studied in 194 conjunctival specimens of 125 preoperative patients without signs of ocular infection. Specimens were evaluated for growth of bacteria on Drigalski's plates, blood agar plates, or chocolate agar plates for 2 days at 37 degrees C. Susceptibilities of the strain to DMPPX, OFLX, minocycline (MINO), gentamicin (GM), erythromycin (EM), cefmenoxime (CMX), chloramphenicol (CP), and sulbenicillin (SBPC) were determined by the disk diffusion method. When DMPPC-resistant Staphylococcus aureus (MRSA) or DMPPC-resistant coagulase- negative staphylococci (MRCNS) were isolated, the susceptibility of the isolated strains to vancomycin (VCM) was additionally examined by the disk diffusion method. Of the 125 preoperative patients (194 eyes), 109 patients (159 eyes) had positive bacterial growth. Methicillin-resistant Staphylococcus aureus (MRSA) were positive in 1 patient. Methicillin-resistant coagulase-negative staphylococci (MRCNS) were positive in another patient. Two eyes with MRSA or MRCNS growth were treated with topical instillation of VCM, whi...Continue Reading

Associated Clinical Trials

Citations

Jun 23, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T Ness
Jun 26, 2013·Experimental Eye Research·Mark D P Willcox
Mar 3, 2009·Journal of Cataract and Refractive Surgery·Yuichi HoriYasuo Tano
Feb 27, 2007·American Journal of Ophthalmology·Renée SolomonRobert K Maloney
Aug 18, 2004·Journal of Cataract and Refractive Surgery·Raneen Shehadeh-Masha'ourHanna J Garzozi

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