PMID: 8971619Dec 1, 1996Paper

Methicillin-resistant Staphylococcus aureus: investigation of a hospital outbreak using a case-control study

The Journal of Hospital Infection
N CrowcroftJ Thomas

Abstract

A retrospective case-control study of 50 MRSA-positive patients was carried out during an outbreak of methicillin-resistant Staphylococcus aureus (MRSA) at an acute general hospital in London. Controls were randomly selected from MRSA-negative patients admitted during the outbreak period. Risk factors investigated included length of admission prior to screening, number of ward changes, main diagnosis, extent of staff contact, pressure sores, surgical and other invasive procedures and antibiotic treatment. Outcome variables examined were rates of infection (versus colonization) with MRSA and mortality. Patients with MRSA were in hospital longer before microbiological specimens were taken and moved wards more often than controls. In a logistic regression analysis, length of stay in hospital, pressure sores, physiotherapy and surgical procedures were associated with a significantly increased risk of acquiring MRSA. Odds ratios (and 95% confidence intervals) for having acquired MRSA were: 8.3 (1.02-71.43) if a patient had pressure sores; 3.7 (1.10-12.5) if they received physiotherapy; and 3.2 (1.82-10.0) if they underwent surgical procedures. The rate of clinical infection amongst patients with this strain of MRSA was 26% and inclu...Continue Reading

References

Sep 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J M BoyceA A Medeiros
Oct 23, 1993·BMJ : British Medical Journal·G J Duckworth
Jan 1, 1994·BMJ : British Medical Journal·P Nair, J Henderson

❮ Previous
Next ❯

Citations

Mar 3, 2004·Computer Methods and Programs in Biomedicine·Kelvin K W YauPhilip J W Carrivick
Sep 4, 2003·Statistics in Medicine·Noor Azina IsmailR A Webster
Jan 11, 2012·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Ioannis G BaraboutisStuart Johnson
Mar 9, 2000·The Journal of Hospital Infection·M MorganA Howard
Feb 5, 2000·The Journal of Hospital Infection·B D Cookson
Nov 27, 1998·The Journal of Hospital Infection·S R ThomasM E Hodson
Sep 25, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·H von BaumConstanze Wendt
Jul 13, 2006·British Journal of Nursing : BJN·Joseph B CunninghamThomas Rush

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Related Papers

The Journal of Hospital Infection
A RahmanB Cookson
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
A AsensioM Martinez-Ferrer
© 2021 Meta ULC. All rights reserved